Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2608934 | 0.78 | PSMB1 (0.47) | SMN1; SMN2NPC1MITFLMNATP53 | |
| SCHEMBL8247965 | 0.75 | POLB (0.43) | SMN1; SMN2NPC1MITFLMNATP53 | |
| SCHEMBL8243279 | 0.75 | NPC1 (0.42) | SMN1; SMN2NPC1MITFLMNATP53 | |
| SCHEMBL12250935 | 0.74 | NPC1 (0.47) | SMN1; SMN2NPC1MITFLMNATP53 | |
| SCHEMBL8242634 | 0.72 | POLB (0.41) | SMN1; SMN2NPC1MITFLMNATP53 | |
| SCHEMBL11613552 | 0.72 | NPC1 (0.53) | SMN1; SMN2NPC1MITFLMNATP53 | |
| Water SCHEMBL9752634 | 0.71 | POLB (0.44) | SMN1; SMN2NPC1MITFLMNATP53 | |
| SCHEMBL30969894 | 0.71 | IDH1 (0.45) | — | |
| SCHEMBL9752577 | 0.71 | POLB (0.46) | POLBNPSR1PSMB1PSMB5KDM4E | |
| SCHEMBL9752710 | 0.71 | POLB (0.46) | SMN1; SMN2NPC1MITFLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106551931-A | Purposes of the 1- hydroxyl -2- pyridine compounds on oral keritonocytes medicine is prepared | 张梦兮 | 2017-04-05 | — | — | CN | claimed |
| US-20240009100-A1 | HAIR CARE COMPOSITIONS COMPRISING A 2-PYRIDINOL-N-OXIDE MATERIAL AND AN IRON CHELATOR | PROCTER & GAMBLE (US) | 2024-01-11 | — | — | US | disclosed |
| US-11801213-B2 | Hair care compositions comprising a 2-pyridinol-N-oxide material and an iron chelator | THE PROCTER & GAMBLE COMPANY (US) | 2023-10-31 | — | — | US | disclosed |
| US-20220387280-A1 | HAIR CARE COMPOSITIONS COMPRISING A 2-PYRIDINOL-N-OXIDE MATERIAL AND AN IRON CHELATOR | PROCTER & GAMBLE (US) | 2022-12-08 | — | — | US | disclosed |
| CN-110087627-A | Composition comprising at least two anionic surfactants, nonionic surfactant and amphoteric surfactant and at least one dandruff removing agent | 莱雅公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-108430443-A | Including anion surfactant, by weight at least 3.5% aliphatic acid and the cosmetic composition of dandruff removing agent | 欧莱雅 | 2018-08-21 | — | — | CN | disclosed |
| CN-107468673-A | Transdermal administration of memantine | LTS勒曼治疗系统股份公司 | 2017-12-15 | — | — | CN | disclosed |
| CN-107028790-A | Sunscreen with reduced fabric staining caused by bis-ethylhexyloxyphenol methoxyphenyl triazine | 拜尔斯道夫股份有限公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-107019650-A | Sunscreen with reduced fabric staining caused by 4- (tert-butyl) -4' -methoxydibenzoylmethane | 拜尔斯道夫股份有限公司 | 2017-08-08 | — | — | CN | disclosed |
| US-20170172873-A1 | PROPELLANT-FREE DEODORANTS AND/OR ANTIPERSPIRANTS HAVING SPECIFIC PRESERVATIVE-AGENT COMBINATIONS | HENKEL AG & CO. KGAA (DE) | 2017-06-22 | — | — | US | disclosed |
| CN-106551803-A | Purposes of the piroctone class compound on the health-care products for preparing prevention oral keritonocytes | 张梦兮 | 2017-04-05 | — | — | CN | disclosed |
| CN-106551931-A | Purposes of the 1- hydroxyl -2- pyridine compounds on oral keritonocytes medicine is prepared | 张梦兮 | 2017-04-05 | — | — | CN | disclosed |
| CN-102481273-B | Antimicrobial aminosalicylic acid derivatives | BASF SE (DE) | 2016-11-30 | — | — | CN | disclosed |
| EP-2083873-A1 | ABSORBENT ARTICLES COMPRISING AN ORGANIC ZINC SALT AND AN ANTI-BACTERIAL AGENT OR ALKALI METAL CHLORIDE OR ALKALINE EARTH METAL CHLORIDE | SCA Hygiene Products AB (SE) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008058564-A1 | ABSORBENT ARTICLES COMPRISING AN ORGANIC ZINC SALT AND AN ANTI-BACTERIAL AGENT OR ALKALI METAL CHLORIDE OR ALKALINE EARTH METAL CHLORIDE | SCA HYGIENE PRODUCTS AB (SE) | 2008-05-22 | — | — | WO | disclosed |
| EP-0226984-A1 | Antimycotic nail varnish | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240009100-A1 | HAIR CARE COMPOSITIONS COMPRISING A 2-PYRIDINOL-N-OXIDE MATERIAL AND AN IRON CHELATOR | PLOD1, DPM1, PNPO | SMN1; SMN2 3533/4885NPC1 2329/4885MITF 730/4885 |
| US-11801213-B2 | Hair care compositions comprising a 2-pyridinol-N-oxide material and an iron chelator | PLOD1, DPM1, PNPO | SMN1; SMN2 3533/4885NPC1 2329/4885MITF 730/4885 |
| US-20220387280-A1 | HAIR CARE COMPOSITIONS COMPRISING A 2-PYRIDINOL-N-OXIDE MATERIAL AND AN IRON CHELATOR | PLOD1, DPM1, PNPO | SMN1; SMN2 3533/4885NPC1 2329/4885MITF 730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.