PLOD1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL2148885	0.53	4/20
SCHEMBL1924749	1.00	3/20
SCHEMBL1925385	1.00	3/20
SCHEMBL523476	0.67	3/20
SCHEMBL340946	0.66	3/20
SCHEMBL3108729	0.64	3/20
SCHEMBL1919299	0.60	3/20
SCHEMBL1062957	0.56	3/20
Phenanthroline (SCHEMBL3130843)	0.56	3/20
SCHEMBL2724408	0.55	3/20
SCHEMBL2851867	0.51	3/20
SCHEMBL341384	0.49	3/20
SCHEMBL1682774	0.49	3/20
SCHEMBL1682776	0.46	3/20
SCHEMBL2262230	0.46	3/20
SCHEMBL340456	0.45	3/20
SCHEMBL2647562	0.42	3/20
SCHEMBL200805	0.73	2/20
SCHEMBL313164	0.68	2/20
SCHEMBL2694778	0.65	2/20

Clinical trials — most relevant to PLOD1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype	PHASE2	ACTIVE_NOT_RECRUITING
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes	PHASE2	UNKNOWN
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers	PHASE2	NOT_YET_RECRUITING
Prolonged Release Pirfenidone Versus Placebo in Compensated Cirrhosis.	PHASE2	COMPLETED
Oral Nitrite for Older Heart Failure Patients	PHASE2	COMPLETED
Hydroxyproline Influence on Oxalate Metabolism	PHASE1/PHASE2	COMPLETED
Mitochondrial Function of Immune Cells in Sepsis	nan	COMPLETED
The Clinical Value of the Nitric Oxide System Components in Asthma and COPD	nan	UNKNOWN
Systemic Markers of Collagen Metabolism and Vitamin C in Smokers and Non-Smokers With Pelvic Organ Prolapse	nan	COMPLETED
ProGo Menopause Wellbeing Study	nan	NOT_YET_RECRUITING
The Effect of Vitamin C on Wound Healing In Mandibular Fracture Patients	nan	COMPLETED
The Relation Between Serum Ascorbic Acid Concentration and Preterm Premature Rupture of Membranes	nan	UNKNOWN
Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions	nan	RECRUITING
Pilot Study of Non-Invasive Assessment of Hepatic And Myocardial Iron Through T2* Magnet Resonance Imaging (MRI) In Patients With Iron Overload	nan	COMPLETED
Clubfoot DNA Repository	nan	COMPLETED
Screening of IDH1 and IDH2 Gene Mutations in Adult Acute Myeloid Leukemia for Possible Targeted Therapy	nan	UNKNOWN
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes	nan	RECRUITING
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract	nan	UNKNOWN
Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and Genotype Phenotype Correlation	nan	COMPLETED
Remote Ischemic Postconditioning Increases HIF-1α Plasma Levels and Improves Cardiac Markers After Cardiac Surgery	nan	COMPLETED
Expression of TET1 Gene in Acute Leukaemia	nan	UNKNOWN
Molecular Mechanisms of Exercise Benefits to Insulin Resistant People	nan	COMPLETED
T1 Mapping of Diffuse Myocardial Fibrosis in Congenital Heart Disease	nan	COMPLETED
Determinants of Early Functional Outcome After Reconstructive Surgery	nan	COMPLETED
Study to Identify the Genetic Variations Associated With Phantom Limb Pain	nan	COMPLETED
Lysine Oxidation in Response to Arginine Supplementation	nan	COMPLETED
Phenotype/Genotype Correlation in a Family With Early Onset Osteoarthritis	nan	COMPLETED
Collagenase Chemonucleolysis vs Percutaneous Endoscopic Lumbar Discectomy (PELD) for Lumbar Disc Herniation	nan	UNKNOWN
Studies of Heritable Disorders of Connective Tissue	nan	COMPLETED
Genetics of Ehlers-Danlos Syndrome	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a PLOD1 binder may also engage these)

Protein	Name	Similarity
Q5R9N3	—	1.000	Q5R9N3 →
O77588	—	1.000	O77588 →
Q9R0E2	—	1.000	Q9R0E2 →
Q811A3	—	1.000	Q811A3 →
Q63321	—	1.000	Q63321 →
P24802	—	0.996	P24802 →
Q9R0B9	—	0.993	Q9R0B9 →
PLOD2	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	0.992	landscape →
Q6NVG7	—	0.987	Q6NVG7 →
Q8IYK4	—	0.986	Q8IYK4 →
A0JPH3	—	0.986	A0JPH3 →
A5PMF6	—	0.981	A5PMF6 →
Q5U309	—	0.981	Q5U309 →
Q5U483	—	0.981	Q5U483 →
Q9V730	—	0.980	Q9V730 →
Q8K1B9	—	0.978	Q8K1B9 →
Q6PA90	—	0.976	Q6PA90 →
Q9NY28	—	0.976	Q9NY28 →
FUCA2	Plasma alpha-L-fucosidase	0.976	landscape →
Q6P1J0	—	0.976	Q6P1J0 →
Q5R5N6	—	0.976	Q5R5N6 →
A3KGW5	—	0.976	A3KGW5 →
Q5RFI5	—	0.975	Q5RFI5 →
Q5IGR6	—	0.975	Q5IGR6 →
Q99KR8	—	0.975	Q99KR8 →
Q6DYE8	—	0.974	Q6DYE8 →
Q5ZLK4	—	0.974	Q5ZLK4 →
Q7Z4N8	—	0.974	Q7Z4N8 →
O77695	—	0.974	O77695 →
Q6AYS4	—	0.974	Q6AYS4 →