Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2024983 | 0.98 | HTT (0.42) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL9872789 | 0.84 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL11443167 | 0.79 | GNAI3 (0.42) | POLBKDM4ECA12CA2CA9 | |
| SCHEMBL244127 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL8684710 | 0.78 | GAA (0.46) | HTTLIPEGAAKDM4EALDH1A1 | |
| SCHEMBL1259794 | 0.77 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL15282042 | 0.77 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL7749096 | 0.77 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL7747487 | 0.77 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL7749230 | 0.77 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099454-A2 | AMINOPYRROLIDINES AS CHEMOKINE RECEPTOR ANTAGONISTS | Abbott Laboratories (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008060621-A2 | AMINOPYRROLIDINES AS CHEMOKINE RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2008-05-22 | — | — | WO | disclosed |