Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206736 | 0.87 | HPGD (0.48) | OPRM1OPRL1SSTR1SSTR4ALDH1A1 | |
| SCHEMBL4084112 | 0.84 | HPGD (0.45) | OPRM1OPRL1SSTR1SSTR4ALDH1A1 | |
| SCHEMBL4052851 | 0.84 | KMT2A (0.48) | OPRM1OPRL1SSTR1SSTR4CTDSP1 | |
| SCHEMBL207438 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL205931 | 0.81 | TSHR (0.40) | OPRM1OPRL1SSTR1SSTR4ALDH1A1 | |
| SCHEMBL207909 | 0.81 | HDAC3 (0.45) | OPRM1SSTR1SSTR4ALDH1A1KMT2A | |
| SCHEMBL205662 | 0.81 | HDAC3 (0.40) | OPRM1OPRL1SSTR1SSTR4ALDH1A1 | |
| SCHEMBL207134 | 0.81 | HPGD (0.43) | SSTR1SSTR4ALDH1A1MEN1KMT2A | |
| SCHEMBL206578 | 0.81 | ALDH1A1 (0.45) | SSTR1SSTR4ALDH1A1KMT2ALMNA | |
| SCHEMBL206288 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |