Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206736 | 0.96 | HPGD (0.48) | HPGDMEN1KMT2ALMNAKDM4E | |
| SCHEMBL208660 | 0.94 | PLAAT3 (0.46) | NPC1RAB9APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL206578 | 0.91 | ALDH1A1 (0.45) | HPGDKMT2ALMNAALDH1A1HDAC3 | |
| SCHEMBL207134 | 0.91 | HPGD (0.43) | HPGDMEN1KMT2ALMNAKDM4E | |
| SCHEMBL206456 | 0.91 | POLB (0.45) | HPGDKMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL207253 | 0.88 | HDAC3 (0.43) | HPGDKMT2AALDH1A1HDAC3HDAC1 | |
| SCHEMBL207909 | 0.88 | HDAC3 (0.45) | HPGDKMT2ALMNAALDH1A1HDAC3 | |
| SCHEMBL206288 | 0.88 | ALDH1A1 (0.50) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL208454 | 0.86 | ALDH1A1 (0.53) | HPGDMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL205912 | 0.86 | HPGD (0.47) | HPGDMEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |