Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.56 |
| ▸ | PPARG | P37231 | 11/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4992982 | 0.99 | PPARA (0.55) | PPARAPPARGPPARDLPAR1LPAR3 | |
| SCHEMBL3963763 | 0.84 | PPARA (0.45) | PPARAPPARGPPARD | |
| SCHEMBL4984036 | 0.78 | PTPN1 (0.62) | PPARAPPARGPPARD | |
| SCHEMBL5721779 | 0.78 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL5721599 | 0.78 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL3962827 | 0.77 | LMNA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL3962823 | 0.77 | LMNA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL5175005 | 0.77 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL3963119 | 0.76 | PPARA (0.59) | PPARAPPARGPPARD | |
| SCHEMBL3964391 | 0.76 | PPARA (0.59) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514471-B2 | Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor α (PPAR) | ASTRAZENECA AB (SE) | 2009-04-07 | — | — | US | disclosed |
| US-20050171204-A1 | Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor alpha (ppar) | ASTRAZENECA AB (SE) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171204-A1 | Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor alpha (ppar) | PPARA, PPARD, PPARG | PPARA 1/4885PPARG 3/4885PPARD 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.