Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230112 | 0.85 | SLC1A1 (0.55) | EPHX1SLC1A1TAAR1IDO1AGXT | |
| SCHEMBL5230103 | 0.85 | SLC1A1 (0.55) | EPHX1SLC1A1TAAR1IDO1AGXT | |
| SCHEMBL7967754 | 0.85 | SLC1A1 (0.55) | EPHX1SLC1A1TAAR1IDO1AGXT | |
| SCHEMBL3191528 | 0.84 | SLC6A4 (0.58) | EPHX1TAAR1IDO1AGXTDPP4 | |
| SCHEMBL7458228 | 0.83 | TAAR1 (0.55) | EPHX1SLC1A1TAAR1IDO1AGXT | |
| SCHEMBL21417631 | 0.81 | SLC1A1 (0.51) | EPHX1SLC1A1TAAR1IDO1AGXT | |
| SCHEMBL3130819 | 0.80 | SLC1A1 (0.50) | SLC1A1TAAR1IDO1AGXTDPP4 | |
| SCHEMBL14478266 | 0.79 | PNMT (0.60) | SLC1A1TAAR1IDO1AGXTSLC6A4 | |
| SCHEMBL1530031 | 0.79 | PNMT (0.60) | SLC1A1TAAR1IDO1AGXTSLC6A4 | |
| SCHEMBL29410132 | 0.79 | PNMT (0.60) | SLC1A1TAAR1IDO1AGXTSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009007259-A | METHOD FOR PRODUCING 6-FLUORO-3-(4-FLUOROBENZYL)-1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVE | KOWA CO | 2009-01-15 | — | — | JP | disclosed |