Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.55 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230103 | 1.00 | SLC1A1 (0.55) | SLC1A1DPP4DPP7TAAR1IDO1 | |
| SCHEMBL5230112 | 1.00 | SLC1A1 (0.55) | SLC1A1DPP4DPP7TAAR1IDO1 | |
| SCHEMBL4076385 | 0.85 | EPHX1 (0.52) | SLC1A1DPP4DPP7TAAR1IDO1 | |
| SCHEMBL4332275 | 0.84 | SLC1A1 (0.48) | SLC1A1DPP4DPP7TAAR1IDO1 | |
| SCHEMBL7458228 | 0.83 | TAAR1 (0.55) | SLC1A1DPP4DPP7TAAR1IDO1 | |
| Hydrochloric Acid SCHEMBL4326709 | 0.82 | SLC1A1 (0.47) | SLC1A1DPP4DPP7TAAR1IDO1 | |
| SCHEMBL21417631 | 0.81 | SLC1A1 (0.51) | SLC1A1DPP4DPP7TAAR1IDO1 | |
| SCHEMBL5058348 | 0.80 | PCNA (0.41) | SLC1A1DPP4DPP7IDO1EPHX1 | |
| SCHEMBL8268878 | 0.80 | PCNA (0.41) | SLC1A1DPP4DPP7IDO1EPHX1 | |
| SCHEMBL3130819 | 0.80 | SLC1A1 (0.50) | SLC1A1DPP4DPP7TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274715-B1 | SEMISYNTHETIC MACROLIDES, USEFUL IN BACTERIAL INFECTIONS TREATMENT AND PREVENTION, HAS LESS POTENTIAL FOR DEVELOPING RESISTANCE, IMPROVED OR MODIFIED PROFILES OF DESIRED GRAM-NEGATIVE ACTIVITY | ABBOTT LABORATORIES | 2001-08-14 | — | — | US | disclosed |
| CN-1244202-A | Tricyclic erythromycin derivatives | ABBOTT LAB (US) | 2000-02-09 | — | — | CN | disclosed |