Taurursodiol

Taurursodiol

SCHEMBL40764

C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 12/20 1.00
NR1H4 Q96RI1 6/20 1.00
SLC10A2 Q12908 3/20 1.00
ABCC4 O15439 2/20 1.00
ABCB11 O95342 2/20 1.00
ENPP2 Q13822 2/20 1.00
PLA2G1B P04054 1/20 1.00
SLC10A1 Q14973 6/20 0.89
VDR P11473 1/20 0.79
NR3C1 P04150 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taurochenodeoxycholate SCHEMBL9152921 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL4411471 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL13094131 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL12917602 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL24001493 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL40763 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL24435723 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL17641266 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL24015433 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL17309129 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5971 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139227-A1 ADIPOSE-DERIVED REGENERATIVE CELL PREPARATIONS BLUE CELL THERAPEUTICS APS (DK) 2026-05-21 US claimed
US-20260131089-A1 DRUG DELIVERY DEVICES AND METHODS FOR ADMINISTERING SUBSTANCES TO A BODY CAVITY BY HETEROGENOUS AEROSOLIZATION FOR TREATMENT OF BINGE-EATING DISORDERS AND/OR OBESITY APTARGROUP, INC. (US) 2026-05-14 US claimed
US-12594388-B2 Device to deliver a predetermined amount of a substance to a natural orifice of the body APTARGROUP, INC. (US) 2026-04-07 US claimed
EP-4704971-A1 GAMMA STIMULATION AND NEUROMODULATOR COMBINATION THERAPY Cognito Therapeutics, Inc. (US) 2026-03-11 EP claimed
US-20260062497-A1 Pharmaceutical Formulation and Dosing Regimen for the Treatment of Amyotrophic Lateral Sclerosis AL-S PHARMA AG (CH) 2026-03-05 US claimed
EP-4262876-B1 COVALENTLY MODIFIED ANTIGENS FOR IMPROVED IMMUNE RESPONSE AND/OR STABILITY DEFENCE THERAPEUTICS INC (CA) 2026-02-25 EP claimed
EP-4695613-A2 METHODS OF MODIFYING NEURONS IN VIVO TO TREAT AND/OR PREVENT AMYOTROPHIC LATERAL SCLEROSIS (ALS) Yale University (US) 2026-02-18 EP claimed
US-12491325-B2 Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization for treatment of binge-eating disorders and/or obesity APTARGROUP, INC. (US) 2025-12-09 US claimed
US-20250302824-A1 IN SITU READY-TO-USE INJECTION FORMULATIONS OF POSACONAZOLE FREE OF CYCLODEXTRIN AND ITS DERIVATIVES Hefei Cosource Pharmaceuticals Co., Ltd (CN) 2025-10-02 US claimed
EP-4608505-A1 ANTIOXIDANT COMPOSITIONS AND METHODS OF USE Sanare Pharmaceuticals Corporation (US) 2025-09-03 EP claimed
US-5324514-A Digestive system disorders DIGESTIVE CARE INC. (US) 1994-06-28 US claimed
US-5302400-A Blending pulverized enzymes and buffers, compacting, drying, coating with acid-resistant polymer DIGESTIVE CARE INC. (US) 1994-04-12 US claimed
EP-0576938-A1 Composition of digestive enzymes and salts of bile acids and process for preparation thereof DIGESTIVE CARE INC. (US) 1994-01-05 EP claimed
EP-0574894-A1 Composition of gastric acid - resistant microspheres containing buffered bile acids DIGESTIVE CARE INC. (US) 1993-12-22 EP claimed
US-5262172-A Microencapsulation with carbonate, bicarbonate and amine buffers DIGESTIVE CARE INC. (US) 1993-11-16 US claimed
US-5260074-A Compositions of digestive enzymes and salts of bile acids and process for preparation thereof DIGESTIVE CARE INC. (US) 1993-11-09 US claimed
EP-0551451-A1 N-ALKYL-TAUROURSODEOXYCHOLIC ACIDS AND THEIR THERAPEUTICALLY ACTIVE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PRODOTTI CHIMICI E ALIMENTARI SPA (IT) 1993-07-21 EP claimed
EP-0513887-A1 N-alkyltauroursodeoxycholic acids and their therapeutically active derivatives, a process for their preparation and pharmaceutical compositions containing them PRODOTTI CHIMICI E ALIMENTARI SPA (IT) 1992-11-19 EP claimed
WO-1992018524-A1 N-ALKYL-TAUROURSODEOXYCHOLIC ACIDS AND THEIR THERAPEUTICALLY ACTIVE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PRODOTTI CHIMICI E ALIMENTARI S.P.A. (IT) 1992-10-29 WO claimed
EP-0359058-A1 2-Hydoxy-N,N,N-trimethyl-ethanaminium salts of 5-beta-cholan-24-oic acid Diamalt GmbH (DE) 1990-03-21 EP claimed