Taurochenodeoxycholate

Taurochenodeoxycholate

SCHEMBL56779

C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 12/20 1.00
NR1H4 Q96RI1 6/20 1.00
SLC10A2 Q12908 3/20 1.00
ABCC4 O15439 2/20 1.00
ABCB11 O95342 2/20 1.00
ENPP2 Q13822 2/20 1.00
PLA2G1B P04054 1/20 1.00
SLC10A1 Q14973 6/20 0.89
VDR P11473 1/20 0.79
NR3C1 P04150 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taurochenodeoxycholate SCHEMBL9152921 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL4411471 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL13094131 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL12917602 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL24001493 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL40763 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL24435723 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL17641266 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL24015433 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL17309129 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4853 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075501-A Application of tauroursodeoxycholic acid in inhibiting alpha-glucosidase activity 2026-05-26 CN claimed
CN-122075500-A Application of pig cholic acid bile acid component in preparation of medicine for treating irritable bowel syndrome 2026-05-26 CN claimed
CN-122056828-A Industrial preparation method of vitamin K1 micelle injection preparation 浙江创新生物有限公司 2026-05-19 CN claimed
CN-122070276-A Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same 人类生物科学股份有限公司 2026-05-19 CN claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
CN-122017068-A Bile acid high-flux detection method based on ultra-high performance liquid chromatography tandem mass spectrometry and application thereof 青岛百谱生物科技有限公司 2026-05-12 CN claimed
CN-122005494-A Lipid nanoparticle modified based on taurochenodeoxycholic acid and preparation method and application thereof 福建普立辰生物技术有限公司 2026-05-12 CN claimed
CN-122017071-A Endogenous substance used as biomarker for alcohol-related liver diseases and control application thereof 中国农业大学 2026-05-12 CN claimed
EP-4721745-A1 COMBINED PRODUCT, SALT AND USE THEREOF Shanghai Henlius Biotech, Inc. (CN) 2026-04-08 EP claimed
EP-4721740-A1 COMBINATION PRODUCT, SALT, AND USE THEREOF IN TREATING NEURODEGENERATIVE DISEASES OR DISORDERS Shanghai Henlius Biotech, Inc. (CN) 2026-04-08 EP claimed
EP-0435926-A1 BILE ACIDS FOR TREATMENT OF VIRAL INFECTIONS FISONS plc (GB) 1991-07-10 EP claimed
US-5010056-A Growth disorders PIERREL SPA (IT) 1991-04-23 US claimed
EP-0365139-A2 Bile acids for the treatment of viral infections FISONS plc (GB) 1990-04-25 EP claimed
WO-1990003172-A2 BILE ACIDS FOR TREATMENT OF VIRAL INFECTIONS FISONS PLC (GB) 1990-04-05 WO claimed
EP-0127535-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING INSULIN HADASSAH MEDICAL ORGANIZATION (IL) 1990-01-03 EP claimed
EP-0301392-A1 Pharmaceutical composition for intranasal administration comprising GH - Releasing hormone, a cholinergic agonist and in case a bile salt Pierrel S.p.A. (IT) 1989-02-01 EP claimed
US-4579730-A ORAL ADMINISTRATION; INSULIN BILE ACID OR SALT AND PROTEASE INHIBITOR HADASSAH MEDICAL ORGANIZATION (IL) 1986-04-01 US claimed
EP-0127535-A2 Pharmaceutical compositions containing insulin HADASSAH MEDICAL ORGANIZATION (IL) 1984-12-05 EP claimed
US-4164573-A INSULIN GALINSKY ALVIN M 1979-08-14 US claimed
US-4158707-A Parenteral preparations HOFFMANN-LA ROCHE INC. (US) 1979-06-19 US claimed