Taurochenodeoxycholate

Taurochenodeoxycholate

SCHEMBL56780

C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 12/20 1.00
NR1H4 Q96RI1 6/20 1.00
SLC10A2 Q12908 3/20 1.00
ABCC4 O15439 2/20 1.00
ABCB11 O95342 2/20 1.00
ENPP2 Q13822 2/20 1.00
PLA2G1B P04054 1/20 1.00
SLC10A1 Q14973 6/20 0.89
VDR P11473 1/20 0.79
NR3C1 P04150 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taurochenodeoxycholate SCHEMBL9152921 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL4411471 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL13094131 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL12917602 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL24001493 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL40763 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL24435723 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL17641266 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL24015433 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11
Taurochenodeoxycholate SCHEMBL17309129 1.00 GPBAR1 (1.00) GPBAR1NR1H4SLC10A2ABCC4ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2258 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139227-A1 ADIPOSE-DERIVED REGENERATIVE CELL PREPARATIONS BLUE CELL THERAPEUTICS APS (DK) 2026-05-21 US claimed
CN-122017071-A Endogenous substance used as biomarker for alcohol-related liver diseases and control application thereof 中国农业大学 2026-05-12 CN claimed
CN-122027303-A Credible cloud security level formalized concept verification system and level assessment method 武汉可信云科技有限公司 2026-05-12 CN claimed
EP-4701625-A2 FORMULATION OF THERAPEUTIC AGENTS FOR IMPROVED PERMEATION Vivtex Corporation (US) 2026-03-04 EP claimed
EP-4262876-B1 COVALENTLY MODIFIED ANTIGENS FOR IMPROVED IMMUNE RESPONSE AND/OR STABILITY DEFENCE THERAPEUTICS INC (CA) 2026-02-25 EP claimed
EP-3350313-B1 DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR (SG) 2025-11-26 EP claimed
US-12473379-B2 Method for obtaining purified bacterial polysaccharides SERUM INSTITUTE OF INDIA PRIVATE LIMITED (IN) 2025-11-18 US claimed
EP-4638478-A1 COVALENTLY-MODIFIED STEROID ACID-PEPTIDES HAVING ENHANCED STABILITY AND/OR BIOLOGICAL ACTIVITY Defence Therapeutics Inc. (CA) 2025-10-29 EP claimed
EP-4610652-A1 YAXAB NANOPORE, NANOPORE SYSTEM COMPRISING SAME AND APPLICATIONS THEREOF Korea Research Institute of Bioscience and Biotechnology (KR) 2025-09-03 EP claimed
US-12370237-B2 Lipopeptides for use in treating liver diseases and cardiovascular diseases RUPRECHT - KARLS - UNIVERSITÄT HEIDELBERG (DE) 2025-07-29 US claimed
US-6040188-A MEASURING HYDROCARBON CONTAMINANTS IN SOIL BY MIXING SAMPLE WITH MIXTURE OF LIPIDS AND BILE SALTS, FORMING MICELLES; ALLOW SAMPLE-LIPID-BILE SALT MIXTURE COMPOSITION TO SEPARATE INTO LIQUID PHASE AND SOLID PHASE; MEASURE CONTAMINANTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-03-21 US claimed
EP-0910411-A1 HYDROPHOBIC PREPARATIONS CONTAINING MEDIUM CHAIN MONOGLYCERIDES Cortecs (UK) Limited (GB) 1999-04-28 EP claimed
US-5853974-A Enhancement of alkaline phosphatase with SDS in chemiluminescent substrates CHIRON CORPORATION (US) 1998-12-29 US claimed
US-5785989-A Compositions and methods of manufacturing of oral dissolvable medicaments UNIVERSITY UTAH RESEARCH FOUNDATION (US) 1998-07-28 US claimed
EP-0832296-A2 ENHANCEMENT OF ALKALINE PHOSPHATASE WITH SDS IN CHEMILUMINESCENT SUBSTRATES AND ENZYME INHIBITION ASSAYS CHIRON CORPORATION (US) 1998-04-01 EP claimed
WO-1998000169-A1 HYDROPHOBIC PREPARATIONS CONTAINING MEDIUM CHAIN MONOGLYCERIDES CORTECS (UK) LIMITED) (GB) 1998-01-08 WO claimed
WO-1996041015-A9 ENHANCEMENT OF ALKALINE PHOSPHATASE WITH SDS IN CHEMILUMINESCENT SUBSTRATES AND ENZYME INHIBITION ASSAYS 1997-02-20 WO claimed
WO-1996041015-A2 ENHANCEMENT OF ALKALINE PHOSPHATASE WITH SDS IN CHEMILUMINESCENT SUBSTRATES AND ENZYME INHIBITION ASSAYS CHIRON CORPORATION (US) 1996-12-19 WO claimed
US-5288498-A Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1994-02-22 US claimed
US-5288497-A Compositions of oral dissolvable medicaments THE UNIVERSITY OF UTAH (US) 1994-02-22 US claimed