Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4253880 | 0.98 | EHMT2 (0.46) | EHMT2ACHELMNAPOLBSMO | |
| SCHEMBL18844475 | 0.83 | BRD4 (0.53) | EHMT2ACHELMNASMOBRD4 | |
| Hydrochloric Acid SCHEMBL28802075 | 0.81 | SIGMAR1 (0.58) | LMNAMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL28330649 | 0.79 | EHMT2 (0.44) | EHMT2ACHELMNASMOMEN1 | |
| SCHEMBL13889204 | 0.75 | CHRM2 (0.50) | EHMT2ACHELMNAPOLBMEN1 | |
| SCHEMBL13317117 | 0.71 | ACHE (0.44) | EHMT2ACHELMNAPOLBMEN1 | |
| SCHEMBL15202275 | 0.71 | ACHE (0.47) | EHMT2ACHELMNAPOLBMEN1 | |
| SCHEMBL1078734 | 0.71 | ACHE (0.47) | EHMT2ACHELMNAPOLBMEN1 | |
| SCHEMBL18789346 | 0.71 | EHMT2 (0.41) | EHMT2ACHELMNASMOBRD4 | |
| SCHEMBL12855709 | 0.70 | CHRM2 (0.50) | EHMT2ACHELMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1536787-A4 | IMIDAZOLE ALKALOIDS FROM LEPIDIUM MEYENII AND METHODS OF USAGE | PURE WORLD BOTAN INC (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-1536787-A2 | IMIDAZOLE ALKALOIDS FROM LEPIDIUM MEYENII AND METHODS OF USAGE | Pure World Botanicals, Inc. (US) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004016216-A3 | IMIDAZOLE ALKALOIDS FROM LEPIDIUM MEYENII AND METHODS OF USAGE | PURE WORLD BOTAN INC (US) | 2004-04-29 | — | — | WO | disclosed |
| WO-2004016216-A2 | IMIDAZOLE ALKALOIDS FROM LEPIDIUM MEYENII AND METHODS OF USAGE | PURE WORLD BOTANICALS, INC. (US) | 2004-02-26 | — | — | WO | disclosed |