SCHEMBL4076598

SCHEMBL4076598

CC(C)O[Si](CBr)(CCc1ccccc1)CCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SIGMAR1 Q99720 4/20 0.35
TSHR P16473 2/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
TRPA1 O75762 1/20 0.34
ALDH1A1 P00352 1/20 0.34
AOC3 Q16853 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4073992 0.83 HPGD (0.42) TDP1NPC1RAB9ASIGMAR1TSHR
SCHEMBL4077993 0.83 NPC1 (0.38) TDP1NPC1RAB9ASIGMAR1TSHR
SCHEMBL4073915 0.83 TDP1 (0.41) TDP1NPC1RAB9ASIGMAR1TSHR
SCHEMBL4077066 0.80 TDP1 (0.45) TDP1NPC1RAB9ATSHRADRA1A
SCHEMBL20658047 0.80 TDP1 (0.43) TDP1NPC1RAB9ASIGMAR1TSHR
SCHEMBL105938 0.78 TAAR1 (0.42) TDP1NPC1RAB9ASIGMAR1TSHR
SCHEMBL4077926 0.77 TDP1 (0.42) TDP1NPC1RAB9ATSHRADRA1A
SCHEMBL14495616 0.77 NPC1 (0.43) TDP1NPC1RAB9ASIGMAR1TSHR
SCHEMBL283951 0.77 TDP1 (0.40) TDP1NPC1RAB9ASIGMAR1TSHR
SCHEMBL4077436 0.75 TDP1 (0.39) TDP1NPC1RAB9ASIGMAR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed