SCHEMBL4073992

SCHEMBL4073992

CC(C)O[Si](CI)(CCc1ccccc1)CCc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.42
ALDH1A1 P00352 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
SIGMAR1 Q99720 4/20 0.35
TSHR P16473 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
AOC3 Q16853 1/20 0.34
MAOA P21397 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4080631 0.83 ALDH1A1 (0.42) HPGDALDH1A1ALOX15ALOX12CASP1
SCHEMBL4077993 0.83 NPC1 (0.38) HPGDALDH1A1NPC1RAB9ATDP1
SCHEMBL4076598 0.83 TDP1 (0.41) ALDH1A1NPC1RAB9ATDP1SIGMAR1
SCHEMBL4082456 0.80 ALDH1A1 (0.46) HPGDALDH1A1ALOX15ALOX12CASP1
SCHEMBL14495616 0.80 NPC1 (0.43) NPC1RAB9ATDP1SIGMAR1TSHR
SCHEMBL20658047 0.80 TDP1 (0.43) HPGDALDH1A1ALOX15ALOX12CASP1
SCHEMBL105938 0.78 TAAR1 (0.42) HPGDALDH1A1ALOX15ALOX12CASP1
SCHEMBL4076369 0.77 ALDH1A1 (0.43) HPGDALDH1A1ALOX15ALOX12CASP1
SCHEMBL283951 0.77 TDP1 (0.40) HPGDALDH1A1ALOX15ALOX12CASP1
SCHEMBL4079216 0.75 HPGD (0.41) HPGDALDH1A1ALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed