SCHEMBL4077926

SCHEMBL4077926

CCO[Si](CBr)(CCc1ccccc1)CCc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.42
KCNH2 Q12809 2/20 0.38
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD1 P21728 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
OPRM1 P35372 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38
ALDH1A1 P00352 2/20 0.35
TP53 P04637 1/20 0.35
TRPA1 O75762 1/20 0.35
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
RAB9A P51151 2/20 0.35
HPGD P15428 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17750059 0.89 TDP1 (0.43) TDP1KCNH2CHRM2HTR1AADRA2A
SCHEMBL4077436 0.86 TDP1 (0.39) TDP1KCNH2CHRM2HTR1AADRA2A
SCHEMBL4082752 0.82 TDP1 (0.42) TDP1KCNH2CHRM2HTR1AADRA2A
SCHEMBL4077832 0.82 TDP1 (0.38) TDP1KCNH2CHRM2HTR1AADRA2A
SCHEMBL4076369 0.82 ALDH1A1 (0.43) TDP1KCNH2CHRM2HTR1AADRA2A
SCHEMBL4077066 0.81 TDP1 (0.45) TDP1KCNH2CHRM2HTR1AADRA2A
SCHEMBL107467 0.81 TDP1 (0.43) TDP1KCNH2CHRM2HTR1AADRA2A
SCHEMBL104845 0.79 TDP1 (0.41) TDP1KCNH2CHRM2HTR1AADRA2A
SCHEMBL6743961 0.78 TDP1 (0.40) TDP1KCNH2CHRM2HTR1AADRA2A
SCHEMBL4076598 0.77 TDP1 (0.41) TDP1ADRA1AALDH1A1TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed