SCHEMBL4077044

SCHEMBL4077044

CO[SiH](CCN(C)C)OC

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1991712 0.83 ALDH1A1 (0.43) ALDH1A1TSHRTDP1CA12CA2
SCHEMBL613797 0.81 ALDH1A1 (0.48) ALDH1A1TSHRTDP1
SCHEMBL12898467 0.73
SCHEMBL31133905 0.73 TDP1 (0.50) ALDH1A1TSHRTDP1
SCHEMBL28331482 0.72 CHRM2 (0.35) CA12CA2CA3CA4CA6
SCHEMBL914852 0.72 MEN1 (0.32)
SCHEMBL28438296 0.71 CYP2C9 (0.47) ALDH1A1TSHRTDP1
SCHEMBL27817396 0.70 MEN1 (0.40)
Trimethylammonium SCHEMBL15015633 0.70
SCHEMBL237926 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7556945-B1 Method for converting sucrose to β-D-glucose SANDIA CORPORATION (US) 2009-07-07 US claimed
US-7264962-B1 Enzymatic cascade bioreactor SANDIA CORPORATION (US) 2007-09-04 US claimed
US-7556945-B1 Method for converting sucrose to β-D-glucose SANDIA CORPORATION (US) 2009-07-07 US disclosed
US-7264962-B1 Enzymatic cascade bioreactor SANDIA CORPORATION (US) 2007-09-04 US disclosed
US-5612438-A Curable siloxane polymers containing integral UV absorbers GENERAL ELECTRIC COMPANY (US) 1997-03-18 US disclosed
EP-0598545-A2 Curable siloxane polymers GENERAL ELECTRIC COMPANY (US) 1994-05-25 EP disclosed
US-5310845-A Adding an amine catalyst to a solution of cosolvent-diluted silyated UV agent and polysiloxane/solvent mixture GENERAL ELECTRIC COMPANY (US) 1994-05-10 US disclosed
US-4483973-A Adhesion promoters for one-component RTV silicone compositions GENERAL ELECTRIC COMPANY (US) 1984-11-20 US disclosed