SCHEMBL4077048

SCHEMBL4077048

OC[C@H]1OC[C@H](O)C[C@@H]1O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 1/20 0.34
THRB P10828 1/20 0.31
LMNA P02545 1/20 0.31
OGA O60502 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL903374 1.00 LGALS3 (0.34) LGALS3THRBLMNAOGA
SCHEMBL13191563 1.00 LGALS3 (0.34) LGALS3THRBLMNAOGA
SCHEMBL4074167 1.00 LGALS3 (0.34) LGALS3THRBLMNAOGA
SCHEMBL14967631 1.00 LGALS3 (0.34) LGALS3THRBLMNAOGA
SCHEMBL23026252 1.00 LGALS3 (0.34) LGALS3THRBLMNAOGA
SCHEMBL24149222 1.00 LGALS3 (0.34) LGALS3THRBLMNAOGA
SCHEMBL903332 1.00 LGALS3 (0.34) LGALS3THRBLMNAOGA
SCHEMBL21312802 1.00 LGALS3 (0.34) LGALS3THRBLMNAOGA
SCHEMBL21312685 1.00 LGALS3 (0.34) LGALS3THRBLMNAOGA
SCHEMBL15161122 1.00 LGALS3 (0.34) LGALS3THRBLMNAOGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60016982-A None JP disclosed
WO-2023144545-A1 SACCHARIDE SENSING SYSTEMS Carbometrics Limited (GB) 2023-08-03 WO disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
WO-2022115477-A1 BCL-XL INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2022-06-02 WO disclosed
WO-2022094731-A1 ANHYDROUS CONCENTRATED HAIR CARE COMPOSITIONS IN THE FORM OF A PASTE EVERIST INC. (CA) 2022-05-12 WO disclosed
WO-2020111229-A1 DRUG DELIVERY SYSTEM USING SOLUTION 国立大学法人京都大学 2020-06-04 WO disclosed
WO-2019214567-A1 SWEETENER AND FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF EPC NATURAL PRODUCTS CO., LTD. (CN) 2019-11-14 WO disclosed
WO-2018106645-A1 β-1,6-GLUCAN THERAPEUTIC ANTIBODY CONJUGATES INNATE BIOTHERAPEUTICS, LLC (US) 2018-06-14 WO disclosed
WO-2017133517-A1 PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF 四川海思科制药有限公司 2017-08-10 WO disclosed
WO-2017075257-A2 HIGH INTENSITY SWEETENERS SENOMYX, INC. (US) 2017-05-04 WO disclosed
US-7560231-B2 Mannitol and glucitol derivatives ROCHE MOLECULAR SYSTEMS, INC. (US) 2009-07-14 US disclosed
EP-1431298-B1 Mannitol and glucitol derivatives ROCHE DIAGNOSTICS GMBH (DE) 2006-03-08 EP disclosed
US-20040157247-A1 Mannitol and glucitol derivatives ROCHE MOLECULAR SYSTEMS, INC (US) 2004-08-12 US disclosed
EP-1431298-A1 Mannitol and glucitol derivatives Roche Diagnostics GmbH (DE) 2004-06-23 EP disclosed
EP-1431297-A1 Mannitol and glucitol derivatives BOEHRINGER MANNHEIM GMBH (DE) 2004-06-23 EP disclosed
JP-S6016982-A GLUCOSE ANALOG AND ITS PREPARATION CHUGAI PHARMACEUT CO LTD 1985-01-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040157247-A1 Mannitol and glucitol derivatives ALDOA, DERA, SORD LGALS3 163/4885THRB 4177/4885LMNA 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.