Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 13/20 | 0.51 |
| ▸ | APOB | P04114 | 12/20 | 0.51 |
| ▸ | SMO | Q99835 | 9/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075186 | 0.86 | SMO (0.56) | MTTPAPOBSMO | |
| SCHEMBL3288828 | 0.83 | MTTP (0.65) | MTTPAPOBSMO | |
| SCHEMBL3289795 | 0.81 | MTTP (0.58) | MTTPAPOBSMO | |
| SCHEMBL3288697 | 0.81 | SMO (0.56) | MTTPAPOBSMO | |
| SCHEMBL5298934 | 0.79 | SMO (0.43) | MTTPAPOBSMO | |
| SCHEMBL4079256 | 0.79 | MTTP (0.40) | MTTPAPOBSMO | |
| SCHEMBL3288869 | 0.79 | MTTP (0.56) | MTTPAPOBSMO | |
| SCHEMBL4079252 | 0.78 | MTTP (0.40) | MTTPAPOBSMO | |
| SCHEMBL3289783 | 0.78 | SMO (0.46) | MTTPAPOBSMO | |
| SCHEMBL3290068 | 0.76 | EPHX2 (0.45) | MTTPAPOBSMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753721-B1 | AROYL-O-PIPERIDINE DERIVATIVES FOR THE TREATMENT OF DIABETES-RELATED PROBLEMS | MERCK PATENT GMBH (DE) | 2009-08-05 | — | — | EP | claimed |