Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 3/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | MTTP | P55157 | 5/20 | 0.43 |
| ▸ | APOB | P04114 | 4/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295205 | 0.91 | MAPT (0.50) | EPHX2SMOCSF1RPDGFRBKIT | |
| SCHEMBL4075186 | 0.89 | SMO (0.56) | SMOMTTPAPOB | |
| SCHEMBL3289503 | 0.86 | EPHX2 (0.49) | EPHX2CSF1RPDGFRBKITDDR1 | |
| SCHEMBL5144228 | 0.83 | EPHX2 (0.45) | EPHX2 | |
| SCHEMBL3289783 | 0.83 | SMO (0.46) | EPHX2SMOMTTPAPOB | |
| SCHEMBL4074915 | 0.82 | APOB (0.51) | EPHX2MTTPAPOB | |
| SCHEMBL5298159 | 0.81 | MAPT (0.44) | MTTPAPOBRXFP1 | |
| SCHEMBL3288828 | 0.81 | MTTP (0.65) | SMOMTTPAPOB | |
| SCHEMBL5145627 | 0.81 | EPHX2 (0.43) | EPHX2SCN10A | |
| SCHEMBL5142098 | 0.81 | KMT2A (0.45) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723358-B2 | Aroyl-O-piperidine derivatives for the treatment of diabetes-related problems | MERCK PATENT GMBH (DE) | 2010-05-25 | — | — | US | claimed |