SCHEMBL4077237

SCHEMBL4077237

C=Cc1c([Si](C)(C)C)c([Si](C)(C)C)c([Si](C)(C)C)c([Si](C)(C)C)c1[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4075554 0.65
SCHEMBL5831499 0.62 ALDH1A1 (0.36)
SCHEMBL6261111 0.58 L3MBTL1 (0.32)
SCHEMBL9838347 0.58
SCHEMBL9243970 0.58
SCHEMBL12978556 0.58
SCHEMBL2360433 0.56
SCHEMBL11541405 0.56 L3MBTL1 (0.30)
SCHEMBL81003 0.56 L3MBTL1 (0.36)
SCHEMBL10893873 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019120-B1 BLOCK COPOLYMERS NIPPON SODA CO (JP) 2016-04-13 EP disclosed
US-8193285-B2 Block copolymers NIPPON SODA CO., LTD. (JP) 2012-06-05 US disclosed
US-20090253867-A1 BLOCK COPOLYMERS NIPPON SODA CO., LTD. (JP) 2009-10-08 US disclosed
EP-2019120-A1 BLOCK COPOLYMERS Nippon Soda Co., Ltd. (JP) 2009-01-28 EP disclosed