Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.56 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | HPN | P05981 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4674925 | 1.00 | GAA (0.63) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL6302459 | 0.89 | ALDH1A1 (0.64) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL696505 | 0.87 | ALDH1A1 (0.68) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL2636629 | 0.87 | ALDH1A1 (0.68) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL696506 | 0.87 | ALDH1A1 (0.68) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL9222436 | 0.87 | GAA (0.64) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL13570656 | 0.85 | LMNA (0.63) | GAAL3MBTL1TSHRALDH1A1MAPT | |
| SCHEMBL10433913 | 0.85 | GAA (0.63) | GAAHPGDL3MBTL1MAPK1TSHR | |
| Hydrochloric Acid SCHEMBL4077466 | 0.85 | ALDH1A1 (0.67) | GAAHPGDL3MBTL1MAPK1TSHR | |
| SCHEMBL31265161 | 0.85 | GAA (0.63) | GAAHPGDL3MBTL1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677456-A | REACTING A PYRROLIDINE(3,4-B)PYRIDINE COMPOUND WITH N-TOSYL-L-PROLYL CHLORIDE IN AN ORGANIC SOLVENT AND WATER; CHROMATOGRAPHY | KOREAN RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-10-14 | — | — | US | claimed |
| WO-2025124698-A1 | ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-19 | — | — | WO | disclosed |
| US-7538245-B2 | Process for the manufacture of an enantiopure compound | SOLVAY S.A. (BE) | 2009-05-26 | — | — | US | disclosed |
| EP-1187835-B1 | OPTICALLY ACTIVE QUINOLINE CARBOXYLIC ACID DERIVATIVES HAVING 7-PYRROLIDINE SUBSTITUTES CAUSING OPTICAL ACTIVITY AND A PROCESS FOR PREPARING THEREOF | DONG WHA PHARM IND CO LTD (KR) | 2007-12-26 | — | — | EP | disclosed |
| EP-1664084-A1 | PROCESS FOR THE MANUFACTURE OF AN ENANTIOPURE COMPOUND | SOLVAY (Société Anonyme) (BE) | 2006-06-07 | — | — | EP | disclosed |
| EP-1546108-A1 | 1,4-SUBSTITUTED CYCLOHEXANE DERIVATIVES | UNIVERSITE DE MONTREAL (CA) | 2005-06-29 | — | — | EP | disclosed |
| WO-2005023838-A1 | PROCESS FOR THE MANUFACTURE OF AN ENANTIOPURE COMPOUND | Solvay (Société Anonyme) (BE) | 2005-03-17 | — | — | WO | disclosed |
| US-20040138272-A1 | 1,4-Substituted cyclohexane derivatives | UNIVERSITE DE MONTREAL (CA) | 2004-07-15 | — | — | US | disclosed |
| US-6753430-B2 | GRAM-POSITIVE BACTERIA; METHICILLINE-RESISTANT STAPHYLOCOCCI; NONPHYTOTOXIC; 1,8-NAPHTHYRI-4-DONE DERIVATIVES | DONG WHA PHARM. IND. CO., LTD (KR) | 2004-06-22 | — | — | US | disclosed |
| WO-2004022541-A1 | 1,4-SUBSTITUTED CYCLOHEXANE DERIVATIVES | UNIVERSITE DE MONTREAL (CA) | 2004-03-18 | — | — | WO | disclosed |
| EP-0677052-A1 | NOVEL QUINOLONE DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-10-18 | — | — | EP | disclosed |
| WO-1995015965-A1 | NOVEL QUINOLONE COMPOUNDS AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-06-15 | — | — | WO | disclosed |
| US-5359076-A | Cyclic aminophenylacetic acid derivatives, process for preparing the same and immune response modulator having the same as an effective ingredient | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| WO-1994014813-A1 | NOVEL QUINOLONE DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1994-07-07 | — | — | WO | disclosed |
| EP-0538477-A1 | NOVEL CYCLIC AMINOPHENYLACETIC ACID DERIVATIVE, PRODUCTION THEREOF, AND IMMUNE RESPONSE MODULATOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-4946844-A | Optically active benzoquinolizine compounds, process for preparing same, and antibacterial preparation containing same as active ingredient | TOKYO TANABE CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0341493-A2 | Optically active pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0323189-A2 | Optically active benzoquinolizine compounds, process for preparing same, and antibacterial preparation containing same as active ingredient | TOKYO TANABE COMPANY LIMITED (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4217284-A | Process for preparation of optically pure lactones from monoesters of cis-cyclopentenediol | KOWA COMPANY LTD. (JP) | 1980-08-12 | — | — | US | disclosed |
| US-4170596-A | Novel monoesters of cis-cyclopentenediol, process for preparation thereof, and process for preparation of lactones from the monoesters | KOWA COMPANY, LTD. | 1979-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138272-A1 | 1,4-Substituted cyclohexane derivatives | ROCK1, RAC1, KSR1 | GAA 2882/4885HPGD 1915/4885L3MBTL1 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.