SCHEMBL407787

SCHEMBL407787

CC(N)(Cc1ccccc1)C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.57
TAAR1 Q96RJ0 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HIF1A Q16665 1/20 0.57
BLM P54132 2/20 0.55
MAPT P10636 3/20 0.48
KMT2A Q03164 2/20 0.48
CYP3A4 P08684 3/20 0.46
RECQL P46063 3/20 0.46
CYP1A2 P05177 2/20 0.46
ALDH1A1 P00352 3/20 0.46
USP2 O75604 2/20 0.46
HPGD P15428 2/20 0.46
ALOX15 P16050 2/20 0.46
HSD17B10 Q99714 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
EGFR P00533 1/20 0.46
FYN P06241 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5268840 1.00 SLC6A2 (0.57) SLC6A2TAAR1SMN1; SMN2HIF1ABLM
SCHEMBL407788 1.00 SLC6A2 (0.57) SLC6A2TAAR1SMN1; SMN2HIF1ABLM
Hydrochloric Acid SCHEMBL28585467 0.98 SLC6A2 (0.55) SLC6A2TAAR1SMN1; SMN2HIF1ABLM
Hydrochloric Acid SCHEMBL28585466 0.98 SLC6A2 (0.55) SLC6A2TAAR1SMN1; SMN2HIF1ABLM
SCHEMBL7403762 0.93 PLA2G10 (0.53) SLC6A2TAAR1SMN1; SMN2HIF1ABLM
SCHEMBL8935465 0.93 BLM (0.53) SLC6A2TAAR1SMN1; SMN2HIF1ABLM
Hydrochloric Acid SCHEMBL27320071 0.87 BLM (0.47) SLC6A2TAAR1SMN1; SMN2HIF1ABLM
SCHEMBL9515271 0.86 BLM (0.46) SLC6A2TAAR1SMN1; SMN2HIF1ABLM
SCHEMBL122295 0.86 BLM (0.72) SLC6A2TAAR1SMN1; SMN2HIF1ABLM
SCHEMBL202327 0.86 BLM (0.72) SLC6A2TAAR1SMN1; SMN2HIF1ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3535310-B1 ACROLEIN SCAVENGING IN PTF AND OTHER 1,3-PROPANEDIOL DERIVED POLYMERS COCA COLA CO (US) 2025-12-24 EP claimed
US-11708454-B2 Acrolein scavenging in PTF and other 1,3-propanediol derived polymers THE COCA-COLA COMPANY (US) 2023-07-25 US claimed
US-20190330420-A1 ACROLEIN SCAVENGING IN PTF AND OTHER 1,3-PROPANEDIOL DERIVED POLYMERS THE COCA-COLA COMPANY (US) 2019-10-31 US claimed
EP-3535310-A1 ACROLEIN SCAVENGING IN PTF AND OTHER 1,3-PROPANEDIOL DERIVED POLYMERS The Coca-Cola Company (US) 2019-09-11 EP claimed
CN-109996830-A Acrolein scavenger in PTF and other 1, 3-propanediol derived polymers 可口可乐公司 2019-07-09 CN claimed
CN-1942179-B Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders NEWRON PHARM SPA 2010-08-11 CN claimed
CN-101466366-A Alpha-aminoamide derivatives for the treatment of cognitive disorders NEWRON PHARM SPA (IT) 2009-06-24 CN claimed
CN-1942179-A Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders NEWRON PHARM SPA (IT) 2007-04-04 CN claimed
EP-3535310-B1 ACROLEIN SCAVENGING IN PTF AND OTHER 1,3-PROPANEDIOL DERIVED POLYMERS COCA COLA CO (US) 2025-12-24 EP disclosed
US-11708454-B2 Acrolein scavenging in PTF and other 1,3-propanediol derived polymers THE COCA-COLA COMPANY (US) 2023-07-25 US disclosed
US-11124482-B2 C-met modulators and methods of use EXELIXIS, INC. (US) 2021-09-21 US disclosed
US-20210253530-A9 C-MET MODULATORS AND METHODS OF USE EXELIXIS, INC. 2021-08-19 US disclosed
US-20200331860-A1 C-Met Modulators and Methods of Use EXELIXIS INC (US) 2020-10-22 US disclosed
US-20190330420-A1 ACROLEIN SCAVENGING IN PTF AND OTHER 1,3-PROPANEDIOL DERIVED POLYMERS THE COCA-COLA COMPANY (US) 2019-10-31 US disclosed
US-6465684-B2 DIASTEREOMER COMPLEX OF AT LEAST THREE COMPOUNDS, AT LEAST ONE IS A RESOLVING AGENT IN OPTICALLY ACTIVE FORM, AND AT LEAST ONE IS AN ENANTIOMER IN OPTICALLY ACTIVE FORM; RAPID SEPARATION DSM N.V. (NL) 2002-10-15 US disclosed
US-20010051747-A1 Process for the separation of a mixture of enantiomers DSM N.V. 2001-12-13 US disclosed
US-6235927-B1 OPTICAL RESOLUTION OF ENANTIOMORPHS OF COMPLEXES DSM N.V. (NL) 2001-05-22 US disclosed
EP-0838448-A1 Process for the separation of a mixture of enantiomers DSM N.V. (NL) 1998-04-29 EP disclosed
EP-0231546-B1 PROCESS FOR THE PREPARATION OF ALPHA-AMINO-ALPHA-METHYLCARBOXYLIC ACID AMIDES AND ALPHA-AMINO-ALPHA-CYCLOALKYLCARBOXYLIC ACID AMIDES STAMICARBON B.V. (NL) 1990-11-07 EP disclosed
EP-0231546-A1 Process for the preparation of alpha-amino-alpha-methylcarboxylic acid amides and alpha-amino-alpha-cycloalkylcarboxylic acid amides STAMICARBON B.V. (NL) 1987-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200331860-A1 C-Met Modulators and Methods of Use FLT4, FLT1, MET SLC6A2 3028/4885TAAR1 3372/4885SMN1; SMN2 4421/4885
US-20210253530-A9 C-MET MODULATORS AND METHODS OF USE FLT4, FLT1, MET SLC6A2 3028/4885TAAR1 3372/4885SMN1; SMN2 4421/4885
US-20010051747-A1 Process for the separation of a mixture of enantiomers EPHX2, VKORC1, ALDH1A2 SLC6A2 4434/4885TAAR1 4282/4885SMN1; SMN2 3530/4885
US-11124482-B2 C-met modulators and methods of use FLT4, FLT1, MET SLC6A2 3028/4885TAAR1 3372/4885SMN1; SMN2 4421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.