Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 9/20 | 0.60 |
| ▸ | HTR1B | P28222 | 6/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | HTR1F | P30939 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4077871 | 1.00 | HTR1D (0.60) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL6478835 | 0.99 | HTR1D (0.59) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL4077699 | 0.90 | HTR1D (0.47) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL4077697 | 0.90 | HTR1D (0.47) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL5538713 | 0.90 | HTR1D (0.54) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL5537756 | 0.89 | HTR6 (0.53) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL5532214 | 0.89 | HTR6 (0.53) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL4087151 | 0.88 | HTR1D (0.62) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL4087159 | 0.88 | HTR1D (0.62) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| Acetic Acid SCHEMBL8931562 | 0.86 | HTR1D (0.54) | HTR1DHTR1BHTR1AKMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563904-B2 | Synthesis intermediates useful for preparing zolmitriptan | INKE, S.A. (ES) | 2009-07-21 | — | — | US | disclosed |
| US-20080306279-A1 | Synthesis Intermediates Useful For Preparing Zolmitriptan | INKE, S.A. (ES) | 2008-12-11 | — | — | US | disclosed |
| US-7342035-B2 | Reduction, acidification of aniline diazonium salt ; In situ reaction of hydrazine hydrochloride with alpha-keto-delta-valerolactone; Fischer indole synthesis of hydrazone; Transesterification of pyranoindolone; Conversion of hydroxyl group into amino; Saponification, decarboxylation of indolecarboxylate | INKE, S.A. (ES) | 2008-03-11 | — | — | US | disclosed |
| EP-1534705-B1 | PROCESS FOR PREPARING ZOLMITRIPTAN COMPOUNDS | INKE SA (ES) | 2006-07-26 | — | — | EP | disclosed |
| US-20060025600-A1 | Process for preparing zolmitriptan compounds | INKE, S.A. (ES) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306279-A1 | Synthesis Intermediates Useful For Preparing Zolmitriptan | CYP51A1, CYP4A11, TPSD1 | HTR1D 334/4885HTR1B 416/4885HTR1A 436/4885 |
| US-20060025600-A1 | Process for preparing zolmitriptan compounds | CYP51A1, CYP4A11, HSD11B1 | HTR1D 236/4885HTR1B 310/4885HTR1A 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.