Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774917 | 0.88 | CYP2C19 (0.35) | CYP2C19CYP1A2CYP2C9TRPA1KDM4E | |
| SCHEMBL465453 | 0.76 | CYP2C19 (0.39) | CYP2C19CYP1A2CYP2C9TRPA1KDM4E | |
| SCHEMBL27847938 | 0.76 | TRPA1 (0.37) | CYP2C19CYP1A2CYP2C9TRPA1KDM4E | |
| SCHEMBL27847935 | 0.76 | TRPA1 (0.37) | CYP2C19CYP1A2CYP2C9TRPA1KDM4E | |
| SCHEMBL6671847 | 0.75 | CYP2C19 (0.42) | CYP2C19CYP1A2CYP2C9TRPA1KDM4E | |
| SCHEMBL27906586 | 0.74 | CYP2C19 (0.46) | CYP2C19CYP1A2CYP2C9KDM4EALDH1A1 | |
| SCHEMBL3887213 | 0.74 | CYP2C19 (0.40) | CYP2C19CYP1A2CYP2C9TRPA1KDM4E | |
| SCHEMBL28181064 | 0.73 | MEN1 (0.37) | CYP2C19CYP1A2CYP2C9TRPA1ALDH1A1 | |
| SCHEMBL28232034 | 0.71 | KDM4E (0.38) | TRPA1KDM4EALDH1A1LMNAHIF1A | |
| SCHEMBL30748517 | 0.71 | AOC3 (0.34) | TRPA1KDM4EALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076503-B1 | C-PHENYL GLYCITOL COMPOUND FOR THE TREATMENT OF DIABETES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2013-07-17 | — | — | EP | claimed |
| JP-2009120553-A | THERAPEUTIC AGENT FOR DIABETES CONTAINING C-PHENYL GLUCITOL COMPOUND AS EFFECTIVE INGREDIENT | TAISHO PHARMACEUTICAL CO LTD | 2009-06-04 | — | — | JP | disclosed |