Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4077896 | 0.88 | CYP2C19 (0.38) | CYP2C19CYP1A2CYP2C9TRPA1ALDH1A1 | |
| SCHEMBL465453 | 0.72 | CYP2C19 (0.39) | CYP2C19CYP1A2CYP2C9TRPA1ALDH1A1 | |
| SCHEMBL17396368 | 0.70 | CPA3 (0.39) | CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL14490195 | 0.69 | CYP2C19 (0.36) | CYP2C19CYP1A2CYP2C9ALDH1A1CYP2D6 | |
| SCHEMBL28181064 | 0.69 | MEN1 (0.37) | CYP2C19CYP1A2CYP2C9TRPA1ALDH1A1 | |
| SCHEMBL27847935 | 0.69 | TRPA1 (0.37) | CYP2C19CYP1A2CYP2C9TRPA1ALDH1A1 | |
| SCHEMBL27847938 | 0.69 | TRPA1 (0.37) | CYP2C19CYP1A2CYP2C9TRPA1ALDH1A1 | |
| SCHEMBL11856881 | 0.67 | CYP2C19 (0.39) | CYP2C19TRPA1ALDH1A1CYP2D6HSD17B10 | |
| SCHEMBL6671847 | 0.67 | CYP2C19 (0.42) | CYP2C19CYP1A2CYP2C9TRPA1ALDH1A1 | |
| SCHEMBL8824986 | 0.67 | CYP1A2 (0.35) | CYP2C19CYP1A2CYP2C9ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036901-B1 | C-PHENYL 1-THIOGLUCITOL COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2013-05-01 | — | — | EP | claimed |
| WO-2008001864-A1 | C-PHENYL 1-THIOGLUCITOL COMPOUND | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-03 | — | — | WO | disclosed |