Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4069649 | 0.89 | SERPINE1 (0.56) | SERPINE1FFAR4RORCHDAC1HDAC8 | |
| SCHEMBL4077970 | 0.88 | SERPINE1 (0.42) | SERPINE1FFAR4RORCHDAC1HDAC8 | |
| SCHEMBL4071552 | 0.85 | SERPINE1 (0.44) | SERPINE1FFAR4RORCHDAC1HDAC8 | |
| SCHEMBL4077703 | 0.85 | PTPN5 (0.45) | SERPINE1HDAC8GPR35MAPTHDAC3 | |
| SCHEMBL4133870 | 0.85 | CNR1 (0.41) | SERPINE1FFAR4RORCNPY5RMAPT | |
| SCHEMBL4133869 | 0.85 | CNR1 (0.41) | SERPINE1FFAR4RORCNPY5RMAPT | |
| SCHEMBL4137978 | 0.82 | GAA (0.43) | MAPT | |
| SCHEMBL3958851 | 0.80 | SERPINE1 (0.51) | SERPINE1FFAR4PTGDR2MAPT | |
| SCHEMBL4072263 | 0.77 | ACLY (0.48) | SERPINE1FFAR4GPR35MAPT | |
| SCHEMBL4069651 | 0.77 | SERPINE1 (0.52) | SERPINE1FFAR4RORCHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | claimed |
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |