Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013506 | 0.95 | HTR6 (0.48) | HTR6 | |
| SCHEMBL1015805 | 0.85 | HTR6 (0.48) | HTR6 | |
| SCHEMBL1015804 | 0.85 | HTR6 (0.48) | HTR6 | |
| SCHEMBL1012565 | 0.83 | HTR6 (0.47) | HTR6 | |
| SCHEMBL1014550 | 0.79 | HTR6 (0.48) | HTR6 | |
| SCHEMBL1015637 | 0.77 | SFRP1 (0.41) | HTR6CCR8 | |
| SCHEMBL1013489 | 0.76 | HTR6 (0.55) | HTR6 | |
| SCHEMBL1015115 | 0.76 | HTR6 (0.55) | HTR6 | |
| SCHEMBL1013490 | 0.76 | HTR6 (0.55) | HTR6 | |
| SCHEMBL1016232 | 0.75 | HTR6 (0.40) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081890-A1 | ARYLSULFONYL PYRROLIDINES AS 5-HT6 INHIBITORS | F. Hoffmann-Roche AG (CH) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008055847-A1 | ARYLSULFONYL PYRROLIDINES AS 5-HT6 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-05-15 | — | — | WO | disclosed |