⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248467 | 1.00 | — | — | |
| SCHEMBL524526 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6345328 | 0.98 | DDAH1 (0.53) | — | |
| Hydrochloric Acid SCHEMBL6345332 | 0.98 | DDAH1 (0.53) | — | |
| Ammonia Solution, Strong SCHEMBL22163822 | 0.98 | DDAH1 (0.53) | — | |
| SCHEMBL30508517 | 0.87 | NOS3 (0.57) | — | |
| SCHEMBL25660351 | 0.86 | DDAH1 (0.60) | — | |
| SCHEMBL6625304 | 0.86 | DDAH1 (0.60) | — | |
| SCHEMBL19460502 | 0.86 | SLC1A1 (0.64) | — | |
| SCHEMBL19460501 | 0.86 | SLC1A1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009529509-A | — | — | 2009-08-20 | — | — | JP | claimed |
| EP-2007791-A2 | MODIFIED MOLECULES WHICH PROMOTE HEMATOPOIESIS | AplaGen GmbH (DE) | 2008-12-31 | — | — | EP | claimed |
| WO-2007101698-A2 | MODIFIED MOLECULES WHICH PROMOTE HEMATOPOIESIS | APLAGEN GMBH (DE) | 2007-09-13 | — | — | WO | claimed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-3087094-B1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | POLYPHOR AG (CH) | 2022-06-01 | — | — | EP | disclosed |
| WO-2021102332-A1 | TGFBETAR2 INHIBITOR-LRRC15 ANTIBODY CONJUGATES AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |
| US-20090281278-A1 | MODIFIED MOLECULES WHICH PROMOTE HEMATOPOIESIS | APLAGEN GMBH (DE) | 2009-11-12 | — | — | US | disclosed |
| EP-2007791-A2 | MODIFIED MOLECULES WHICH PROMOTE HEMATOPOIESIS | AplaGen GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007101698-A2 | MODIFIED MOLECULES WHICH PROMOTE HEMATOPOIESIS | APLAGEN GMBH (DE) | 2007-09-13 | — | — | WO | disclosed |
| US-7253194-B2 | Compounds and inhibitors of phospholipases | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-08-07 | — | — | US | disclosed |