Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 3/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13901272 | 0.99 | TLR2 (0.42) | ALDH1A1LMNATLR2PRKCAPRKCE | |
| SCHEMBL4077674 | 0.91 | ALDH1A1 (0.48) | ALDH1A1LMNATLR2PRKCAPRKCE | |
| SCHEMBL4081060 | 0.84 | MAPK1 (0.44) | ALDH1A1LMNATLR2PRKCAPRKCE | |
| SCHEMBL13901190 | 0.81 | CYP1A2 (0.42) | ALDH1A1LMNATLR2PRKCAPRKCE | |
| SCHEMBL25873835 | 0.81 | TLR2 (0.41) | ALDH1A1LMNATLR2L3MBTL1 | |
| SCHEMBL25874010 | 0.81 | TLR2 (0.41) | ALDH1A1LMNATLR2L3MBTL1 | |
| SCHEMBL25474578 | 0.80 | ALDH1A1 (0.68) | ALDH1A1LMNATLR2PRKCAPRKCE | |
| SCHEMBL1117789 | 0.80 | ALDH1A1 (0.68) | ALDH1A1LMNATLR2PRKCAPRKCE | |
| SCHEMBL23668333 | 0.80 | ALDH1A1 (0.68) | ALDH1A1LMNATLR2PRKCAPRKCE | |
| SCHEMBL20714687 | 0.80 | ALDH1A1 (0.68) | ALDH1A1LMNATLR2PRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507859-B2 | Functional synthetic molecules and macromolecules for gene delivery | FIFTH BASE LLC (US) | 2009-03-24 | — | — | US | disclosed |
| EP-1644479-A4 | FUNCTIONAL SYNTHETIC MOLECULES AND MACROMOLECULES FOR GENE DELIVERY | GRINSTAFF MARK W (US) | 2008-04-23 | — | — | EP | disclosed |
| US-20060241071-A1 | Functional synthetic molecules and macromolecules for gene delivery | FIFTH BASE LLC | 2006-10-26 | — | — | US | disclosed |
| EP-1644479-A2 | FUNCTIONAL SYNTHETIC MOLECULES AND MACROMOLECULES FOR GENE DELIVERY | Grinstaff, Mark, W. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005007810-A2 | FUNCTIONAL SYNTHETIC MOLECULES AND MACROMOLECULES FOR GENE DELIVERY | GRINSTAFF MARK W (US) | 2005-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241071-A1 | Functional synthetic molecules and macromolecules for gene delivery | ANXA6, STING1, POLRMT | ALDH1A1 3722/4885LMNA 953/4885TLR2 2383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.