Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 14/20 | 0.62 |
| ▸ | MMP2 | P08253 | 5/20 | 0.59 |
| ▸ | MMP9 | P14780 | 5/20 | 0.59 |
| ▸ | MMP8 | P22894 | 5/20 | 0.59 |
| ▸ | MMP13 | P45452 | 4/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079440 | 1.00 | BMP1 (0.62) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL2860679 | 0.97 | BMP1 (0.64) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL2860686 | 0.97 | BMP1 (0.64) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL2855090 | 0.92 | MMP2 (0.71) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2855092 | 0.92 | MMP2 (0.71) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2860130 | 0.91 | BMP1 (0.62) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL2860128 | 0.91 | BMP1 (0.62) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL4071426 | 0.90 | BMP1 (0.71) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL4071435 | 0.90 | BMP1 (0.71) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL2854368 | 0.90 | MMP2 (0.56) | BMP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085379-A1 | Arylsulfonamido-substituted hydroxamic acid derivatives | Novartis AG (CH) | 2009-08-05 | — | — | EP | claimed |
| EP-1202961-A1 | ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | Novartis AG (CH) | 2002-05-08 | — | — | EP | claimed |
| WO-2001010827-A1 | ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2001-02-15 | — | — | WO | claimed |
| EP-2085379-A1 | Arylsulfonamido-substituted hydroxamic acid derivatives | Novartis AG (CH) | 2009-08-05 | — | — | EP | disclosed |