SCHEMBL4079596

SCHEMBL4079596

O=CCCC(=O)CCCCCCCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.56
KMT2A Q03164 2/20 0.56
LMNA P02545 3/20 0.55
TSHR P16473 1/20 0.55
NFKB1 P19838 1/20 0.55
PMP22 Q01453 1/20 0.55
ABCC4 O15439 1/20 0.50
FNTA P49354 1/20 0.47
FNTB P49356 1/20 0.47
GPR84 Q9NQS5 1/20 0.46
FFAR1 O14842 1/20 0.46
FFAR4 Q5NUL3 1/20 0.46
FOLH1 Q04609 1/20 0.46
TERT O14746 3/20 0.45
PTPN1 P18031 3/20 0.45
PPARG P37231 3/20 0.45
PPARD Q03181 3/20 0.45
PPARA Q07869 3/20 0.45
BLM P54132 2/20 0.45
HSD17B10 Q99714 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4078931 0.93 FNTA (0.53) MAPTKMT2ALMNATSHRNFKB1
SCHEMBL27627541 0.91 MAPT (0.56) MAPTKMT2ALMNATSHRNFKB1
SCHEMBL21777677 0.86 TSHR (0.44) MAPTKMT2ALMNATSHRABCC4
SCHEMBL27438605 0.85 ACE (0.52) MAPTKMT2ALMNATSHRNFKB1
SCHEMBL737139 0.85 ACE (0.52) MAPTKMT2ALMNATSHRNFKB1
SCHEMBL17744969 0.83 LMNA (0.63) MAPTKMT2ALMNATSHRNFKB1
SCHEMBL648618 0.83 LMNA (0.63) MAPTKMT2ALMNATSHRNFKB1
SCHEMBL1603841 0.83 LMNA (0.63) MAPTKMT2ALMNATSHRNFKB1
SCHEMBL274867 0.83 LMNA (0.63) MAPTKMT2ALMNATSHRNFKB1
SCHEMBL14798059 0.83 LMNA (0.63) MAPTKMT2ALMNATSHRNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3028049-B1 DIAGNOSTIC TOOLS FOR ALZHEIMER'S DISEASE PHARNEXT (FR) 2019-03-20 EP claimed
US-20160195547-A1 DIAGNOSTIC TOOLS FOR ALZHEIMER'S DISEASE PHARNEXT (FR) 2016-07-07 US claimed
EP-3028049-A2 DIAGNOSTIC TOOLS FOR ALZHEIMER'S DISEASE Pharnext (FR) 2016-06-08 EP claimed
WO-2015014903-A2 DIAGNOSTIC TOOLS FOR ALZHEIMER'S DISEASE PHARNEXT (FR) 2015-02-05 WO claimed
EP-0155392-A2 Improved processes for preparing 7-(2-hexyl-5-hydroxy-cyclopentyl)-heptanoic acid IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) 1985-09-25 EP claimed
EP-3028049-B1 DIAGNOSTIC TOOLS FOR ALZHEIMER'S DISEASE PHARNEXT (FR) 2019-03-20 EP disclosed
US-20180275144-A1 DIAGNOSTIC TOOLS FOR ALZHEIMER'S DISEASE PHARNEXT (FR) 2018-09-27 US disclosed
US-20170176470-A1 DETECTION OF CARBOXYALKYLPYRROLE OR PENTYLPYRROLE ETHANOLAMINE PHOSPHOLIPIDS UNIV CASE WESTERN RESERVE (US) 2017-06-22 US disclosed
WO-2016124574-A1 DIAGNOSTIC TOOLS FOR ALZHEIMER'S DISEASE PHARNEXT (FR) 2016-08-11 WO disclosed
US-20160195547-A1 DIAGNOSTIC TOOLS FOR ALZHEIMER'S DISEASE PHARNEXT (FR) 2016-07-07 US disclosed
EP-3028049-A2 DIAGNOSTIC TOOLS FOR ALZHEIMER'S DISEASE Pharnext (FR) 2016-06-08 EP disclosed
WO-2015014903-A2 DIAGNOSTIC TOOLS FOR ALZHEIMER'S DISEASE PHARNEXT (FR) 2015-02-05 WO disclosed
US-20080160505-A1 DIAGNOSTIC METHODS FOR AGE RELATED MACULAR DEGENERATION THE CLEVELAND CLINIC FOUNDATION 2008-07-03 US disclosed
US-7341839-B2 Diagnostic methods for age related macular degeneration THE CLEVELAND CLINIC FOUNDATION (US) 2008-03-11 US disclosed
US-20070072241-A1 diagnosing age-related macular degeneration comprising determining the level of anti-2-( omega -carboxyethyl) pyrrole (CEP) antibodies in a bodily fluid obtained from the test subject NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-03-29 US disclosed
US-7172874-B2 Diagnostic methods for age related macular degeneration THE CLEVELAND CLINIC FOUNDATION (US) 2007-02-06 US disclosed
US-20040265924-A1 Diagnostic methods for age related macular degeneration THE CLEVELAND CLINIC FOUNDATION 2004-12-30 US disclosed
EP-0155392-B1 IMPROVED PROCESSES FOR PREPARING 7-(2-HEXYL-5-HYDROXY-CYCLOPENTYL)-HEPTANOIC ACID IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) 1990-05-02 EP disclosed
US-4894473-A MULTISTAGE, REACTION OF AZELAIC ACID MONOESTER, 9-KETONE-12-NITRODECANOIC ACID, METHYL ESTER INTERMEDIATES ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.P.A. (IT) 1990-01-16 US disclosed
EP-0155392-A2 Improved processes for preparing 7-(2-hexyl-5-hydroxy-cyclopentyl)-heptanoic acid IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) 1985-09-25 EP disclosed