SCHEMBL21777677

SCHEMBL21777677

O=CCCCCCC(=O)CCC=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
HIF1A Q16665 1/20 0.43
FAAH O00519 5/20 0.39
TRPV1 Q8NER1 1/20 0.39
MAPT P10636 5/20 0.38
KMT2A Q03164 2/20 0.38
ABCC4 O15439 1/20 0.38
TERT O14746 3/20 0.34
BLM P54132 2/20 0.34
HSD17B10 Q99714 2/20 0.34
FABP4 P15090 2/20 0.34
F7 P08709 2/20 0.34
F3 P13726 2/20 0.34
GMNN O75496 1/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
POLB P06746 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25240636 0.95 TSHR (0.48) TSHRHIF1AFAAHTRPV1MAPT
SCHEMBL10406439 0.92 HIF1A (0.50) TSHRHIF1AFAAHTRPV1MAPT
SCHEMBL4079596 0.86 MAPT (0.56) TSHRFAAHMAPTKMT2AABCC4
SCHEMBL30497477 0.86 GPR84 (0.46) TSHRHIF1AFAAHTRPV1MAPT
SCHEMBL12855872 0.86 GPR84 (0.46) TSHRHIF1AFAAHTRPV1MAPT
SCHEMBL27627541 0.86 MAPT (0.56) TSHRFAAHMAPTKMT2AABCC4
SCHEMBL21590063 0.84 TSHR (0.70) TSHRFAAHTRPV1MAPTKMT2A
SCHEMBL22749396 0.84 TSHR (0.70) TSHRFAAHTRPV1MAPTKMT2A
SCHEMBL18584643 0.84 TSHR (0.70) TSHRFAAHTRPV1MAPTKMT2A
SCHEMBL23855776 0.84 TSHR (0.70) TSHRFAAHTRPV1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250223639-A1 PROCESS FOR COGNATE NUCLEOTIDE DETECTION IN A NUCLEIC ACID SEQUENCING WORKFLOW PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2025-07-10 US disclosed
US-12344890-B2 Process for cognate nucleotide detection in a nucleic acid sequencing workflow PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2025-07-01 US disclosed
EP-3843842-A1 CARDIAC SARCOMERE INHIBITORS Cytokinetics, Inc. (US) 2021-07-07 EP disclosed
WO-2020047447-A1 CARDIAC SARCOMERE INHIBITORS CYTOKINETICS, INC. (US) 2020-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250223639-A1 PROCESS FOR COGNATE NUCLEOTIDE DETECTION IN A NUCLEIC ACID SEQUENCING WORKFLOW RNGTT, POLRMT, POLM TSHR 2662/4885HIF1A 4574/4885FAAH 4719/4885
US-12344890-B2 Process for cognate nucleotide detection in a nucleic acid sequencing workflow RNGTT, POLRMT, POLM TSHR 2662/4885HIF1A 4574/4885FAAH 4719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.