Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941005 | 0.87 | TSHR (0.67) | TSHRALOX5IDO1AGXTALDH1A1 | |
| SCHEMBL15869122 | 0.82 | TSHR (0.54) | TSHRALOX5TK1IDO1TP53 | |
| SCHEMBL12763795 | 0.82 | TSHR (0.54) | TSHRALOX5TK1IDO1TP53 | |
| SCHEMBL6290708 | 0.82 | TSHR (0.54) | TSHRALOX5TK1IDO1AGXT | |
| SCHEMBL15869125 | 0.82 | TSHR (0.54) | TSHRALOX5TK1IDO1TP53 | |
| SCHEMBL28140657 | 0.81 | TSHR (0.48) | TSHRALOX5TK1IDO1ALDH1A1 | |
| SCHEMBL4069935 | 0.81 | TSHR (0.58) | TSHRALOX5TK1IDO1AGXT | |
| SCHEMBL4079459 | 0.80 | TSHR (0.52) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL28764214 | 0.79 | TSHR (0.56) | TSHRALOX5IDO1AGXTALDH1A1 | |
| SCHEMBL27529664 | 0.79 | TSHR (0.56) | TSHRALOX5TK1IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111793060-A | NLRP3 modulators | 先天肿瘤免疫公司 | 2020-10-20 | — | — | CN | disclosed |
| CN-110914258-A | NLRP3 modulators | 先天肿瘤免疫公司 | 2020-03-24 | — | — | CN | disclosed |
| EP-1670460-B1 | PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2014-11-26 | — | — | EP | disclosed |
| CN-101910183-A | Preparation method of 4- (substituted phenyl) hexahydropyrido [2,1-C ] [1,4] oxazin-6-one | EISAI R&D MAN CO LTD | 2010-12-08 | — | — | CN | disclosed |
| US-7517900-B2 | Pyrazole derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-14 | — | — | US | disclosed |
| CN-100366605-C | Compounds to treat alzheimer's disease | ELAN PHARM INC (US) | 2008-02-06 | — | — | CN | disclosed |
| CN-101090883-A | Substituted hydroxyethylamines | ELAN PHARM INC (US) | 2007-12-19 | — | — | CN | disclosed |
| CN-1989120-A | Guanidine derivatives and their therapeutic use | MERCK PATENT GMBH (DE) | 2007-06-27 | — | — | CN | disclosed |
| CN-1759095-A | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARM INC (US) | 2006-04-12 | — | — | CN | disclosed |
| US-20050080087-A1 | Pyrazole derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2005-04-14 | — | — | US | disclosed |
| US-5919928-A | Phenanthridine derivatives and metal complexes thereof used for transparent recording medium or optical recording medium | NIPPON PAPER INDUSTRIES, CO., LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| US-5892042-A | OPTICAL RECORDING MEDIA WITH ACRIDINE DYES ON TRANSPARENT SUBSTRATE | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| US-5792863-A | HAVING LARGE ABSORPTION IN NEAR INFRARED, REDUCED ABSORPTION IN VISIBLE RANGE | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0318032-B1 | THERMAL DYE TRANSFER SHEET | MITSUBISHI KASEI CORPORATION (JP) | 1993-04-14 | — | — | EP | disclosed |
| EP-0318034-B1 | THERMAL DYE TRANSFER SHEET | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-4988666-A | COPIES, YELLOW QUINOLINE DYE DISPERSED ON A MULTILAYER ELEMENT | MITSUBISHI KASEI CORPORATION (JP) | 1991-01-29 | — | — | US | disclosed |
| US-4954478-A | Magenta dye dispersed in binder; colorfastness | MATSUSHITA ELECTRIC INDUSTRIAL CO. LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0318032-A2 | Thermal dye transfer sheet | MITSUBISHI KASEI CORPORATION (JP) | 1989-05-31 | — | — | EP | disclosed |
| EP-0318034-A1 | Thermal dye transfer sheet | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1989-05-31 | — | — | EP | disclosed |
| US-4820685-A | COLOR LAYER OF QUINOLINE DYES AND BINDERS, ON FILM BASE | MITSUBISHI KASEI CORPORATION (JP) | 1989-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080087-A1 | Pyrazole derivatives as cannabinoid receptor modulators | CNR1, CNR2, NPY1R | TSHR 526/4885ALOX5 1136/4885TK1 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.