Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1414217 | 0.87 | L3MBTL1 (0.49) | TSHRTDP1L3MBTL1NAAAALDH1A1 | |
| SCHEMBL15869130 | 0.83 | TSHR (0.50) | TSHRTDP1L3MBTL1NAAAALDH1A1 | |
| SCHEMBL16878886 | 0.83 | TSHR (0.50) | TSHRTDP1L3MBTL1NAAAALDH1A1 | |
| SCHEMBL16878885 | 0.83 | TSHR (0.50) | TSHRTDP1L3MBTL1NAAAALDH1A1 | |
| SCHEMBL1923696 | 0.82 | TSHR (0.54) | TSHRTDP1L3MBTL1NAAAALDH1A1 | |
| SCHEMBL27811388 | 0.81 | TSHR (0.48) | TSHRTDP1L3MBTL1NAAAALDH1A1 | |
| SCHEMBL27646015 | 0.81 | TSHR (0.52) | TSHRNAAAHTTSMN1; SMN2CA1 | |
| SCHEMBL4055858 | 0.80 | TSHR (0.56) | TSHRTDP1L3MBTL1NAAAALDH1A1 | |
| SCHEMBL1867995 | 0.80 | TSHR (0.56) | TSHRTDP1L3MBTL1NAAAALDH1A1 | |
| SCHEMBL4079622 | 0.80 | TSHR (0.56) | TSHRTDP1L3MBTL1ALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106336384-A | Synthetic method for forming oxazolidine-4-ketone | 杭州师范大学 | 2017-01-18 | — | — | CN | claimed |
| CN-111793060-B | NLRP3 modulators | 先天肿瘤免疫公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-111892577-A | Compounds and methods for targeted degradation of androgen receptor | 阿尔维纳斯运营股份有限公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-111793060-A | NLRP3 modulators | 先天肿瘤免疫公司 | 2020-10-20 | — | — | CN | disclosed |
| CN-111212835-A | Compounds and methods for targeted degradation of androgen receptors | 阿尔维纳斯运营股份有限公司 | 2020-05-29 | — | — | CN | disclosed |
| CN-110914258-A | NLRP3 modulators | 先天肿瘤免疫公司 | 2020-03-24 | — | — | CN | disclosed |
| CN-106336384-A | Synthetic method for forming oxazolidine-4-ketone | 杭州师范大学 | 2017-01-18 | — | — | CN | disclosed |
| EP-1670460-B1 | PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2014-11-26 | — | — | EP | disclosed |
| US-7517900-B2 | Pyrazole derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-14 | — | — | US | disclosed |
| US-20050080087-A1 | Pyrazole derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080087-A1 | Pyrazole derivatives as cannabinoid receptor modulators | CNR1, CNR2, NPY1R | TSHR 526/4885TDP1 4156/4885L3MBTL1 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.