Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | OGG1 | O15527 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2833538 | 0.82 | CA1 (0.62) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL14966662 | 0.81 | L3MBTL1 (1.00) | L3MBTL1CYP3A4ALDH1A1MAPTKDM4E | |
| SCHEMBL2832427 | 0.80 | MAPT (0.71) | LMNAMAPTKDM4EPOLBMEN1 | |
| SCHEMBL4071505 | 0.80 | MPO (0.50) | L3MBTL1MPOCYP3A4KDM5ABLM | |
| SCHEMBL16612086 | 0.79 | MPO (0.57) | L3MBTL1MPOCYP3A4KDM5ABLM | |
| SCHEMBL4072414 | 0.77 | MPO (0.47) | L3MBTL1MPOCYP3A4KDM5ABLM | |
| Hydrochloric Acid SCHEMBL17203100 | 0.77 | MPO (0.55) | L3MBTL1MPOCYP3A4KDM5ABLM | |
| SCHEMBL7101981 | 0.77 | HDAC1 (0.80) | L3MBTL1ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL2924725 | 0.77 | CACNA1B (0.65) | L3MBTL1MPOCYP3A4KDM5ABLM | |
| SCHEMBL343630 | 0.77 | MPO (0.80) | L3MBTL1MPOCYP3A4KDM5ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |