Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074077 | 0.92 | OPRM1 (0.51) | OPRM1OPRL1NPC1RAB9AEPHX2 | |
| SCHEMBL4074080 | 0.89 | OPRM1 (0.51) | OPRM1OPRL1NPC1RAB9AEPHX2 | |
| SCHEMBL4079677 | 0.88 | OPRM1 (0.47) | OPRM1OPRL1NPC1RAB9AEPHX2 | |
| SCHEMBL4079674 | 0.85 | OPRM1 (0.45) | OPRM1OPRL1NPC1RAB9AEPHX2 | |
| SCHEMBL4084421 | 0.82 | OPRM1 (0.45) | OPRM1OPRL1NPC1RAB9AALDH1A1 | |
| SCHEMBL4085419 | 0.82 | OPRM1 (0.45) | OPRM1OPRL1NPC1RAB9AEPHX2 | |
| SCHEMBL251239 | 0.81 | OPRM1 (0.44) | OPRM1OPRL1NPC1EPHX2ALDH1A1 | |
| SCHEMBL251283 | 0.81 | OPRM1 (0.44) | OPRM1OPRL1NPC1RAB9AEPHX2 | |
| SCHEMBL208044 | 0.80 | MEN1 (0.43) | OPRM1OPRL1ALDH1A1TSHR | |
| SCHEMBL209213 | 0.79 | OPRM1 (0.41) | OPRM1OPRL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |