Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | BLK | P51451 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008830 | 0.94 | ALDH1A1 (0.70) | KDM4EALDH1A1PTGS1HSD17B10MAPT | |
| SCHEMBL1843940 | 0.91 | PTGS1 (0.56) | KDM4EALDH1A1PTGS1HSD17B10MAPT | |
| SCHEMBL1275245 | 0.88 | KCNK3 (0.50) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL406940 | 0.85 | PTGS1 (0.51) | KDM4EALDH1A1PTGS1HSD17B10MAPT | |
| SCHEMBL19240497 | 0.85 | PTGS1 (0.54) | KDM4EALDH1A1PTGS1HSD17B10SMN1; SMN2 | |
| SCHEMBL404470 | 0.85 | PTGS1 (0.51) | KDM4EALDH1A1PTGS1HSD17B10MAPT | |
| SCHEMBL2007524 | 0.83 | PTGS1 (0.49) | KDM4EALDH1A1PTGS1HSD17B10MAPT | |
| SCHEMBL1274944 | 0.83 | HDAC3 (0.40) | KDM4EALDH1A1PTGS1HSD17B10MAPT | |
| SCHEMBL3025979 | 0.82 | MAPT (0.43) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL1274926 | 0.82 | MAPT (0.39) | KDM4EALDH1A1HSD17B10MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541473-B2 | 3-aminoxalyl-aminobenzamide derivatives and insecticidal and miticidal agents containing same as active ingredient | AGRO-KANESHO CO., LTD. (JP) | 2013-09-24 | — | — | US | disclosed |
| US-8389767-B2 | Processes and compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389767-B2 | Processes and compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389767-B2 | Processes and compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| EP-2535327-A1 | Insecticidal 3-acylaminobenzanilides | Bayer CropScience AG (DE) | 2012-12-19 | — | — | EP | disclosed |
| US-20120022263-A1 | 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT | AGRO-KANESHO CO., LTD. (JP) | 2012-01-26 | — | — | US | disclosed |
| US-7964735-B2 | Insecticidal 3-acylaminobenzanilides | BAYER CROPSCIENCE AG (DE) | 2011-06-21 | — | — | US | disclosed |
| US-20100204504-A1 | NOVEL PROCESSES AND COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20100204504-A1 | NOVEL PROCESSES AND COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20100204504-A1 | NOVEL PROCESSES AND COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| EP-2183212-A1 | NOVEL PROCESSES AND COMPOUNDS | Syngenta Participations AG (CH) | 2010-05-12 | — | — | EP | disclosed |
| US-20090215623-A1 | Insecticidal 3-acylaminobenzanilides | BAYER CROPSCIENCE AG (DE) | 2009-08-27 | — | — | US | disclosed |
| WO-2009030457-A1 | NOVEL PROCESSES AND COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-03-12 | — | — | WO | disclosed |
| WO-2009030457-A1 | NOVEL PROCESSES AND COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-03-12 | — | — | WO | disclosed |
| EP-1912933-A1 | INSECTICIDAL 3-ACYLAMINOBENZANILIDES | Bayer CropScience AG (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017075-A1 | INSECTICIDAL 3-ACYLAMINOBENZANILIDES | BAYER CROPSCIENCE AG (DE) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022263-A1 | 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT | HDHD5, CBR3, BAK1 | KDM4E 399/4885ALDH1A1 889/4885PTGS1 3471/4885 |
| US-20090215623-A1 | Insecticidal 3-acylaminobenzanilides | CBR3, AADAC, DDT | KDM4E 1914/4885ALDH1A1 1739/4885PTGS1 4123/4885 |
| US-20100204504-A1 | NOVEL PROCESSES AND COMPOUNDS | DDT, CYP4B1, CYP4F3 | KDM4E 1085/4885ALDH1A1 351/4885PTGS1 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.