Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524975 | 0.91 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ACA1MAPTMEN1 | |
| SCHEMBL3527455 | 0.90 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ACA1MAPTMEN1 | |
| SCHEMBL4079438 | 0.69 | RAB9A (0.60) | SMN1; SMN2RAB9ACA1MAPTMEN1 | |
| SCHEMBL2556201 | 0.68 | RAB9A (0.74) | SMN1; SMN2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL3863110 | 0.68 | RAB9A (0.57) | SMN1; SMN2RAB9ACA1MAPTMEN1 | |
| SCHEMBL244380 | 0.67 | L3MBTL1 (0.58) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL4075394 | 0.67 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ACA1MAPTMEN1 | |
| SCHEMBL19297530 | 0.67 | RAB9A (0.45) | RAB9AMEN1KMT2ANPC1LMNA | |
| SCHEMBL3863210 | 0.66 | CA1 (0.49) | SMN1; SMN2RAB9ACA1MAPTMEN1 | |
| SCHEMBL12288921 | 0.65 | RAB9A (1.00) | SMN1; SMN2RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021309-A1 | IMIDAZOLIDIN-2-ONE DERIVATIVES USEFUL AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |