Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Docosanol SCHEMBL28032775 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2AHSPD1 | |
| Cetyl Alcohol SCHEMBL27695077 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2AHSPD1 | |
| Citric Acid SCHEMBL28592430 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2AHSPD1 | |
| Citric Acid SCHEMBL28592422 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2AHSPD1 | |
| Octacosanol SCHEMBL27695196 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2AHSPD1 | |
| Citric Acid SCHEMBL23043753 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2AHSPD1 | |
| Cetostearyl Alcohol SCHEMBL8679742 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2AHSPD1 | |
| Citric Acid SCHEMBL28887780 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2AHSPD1 | |
| Citric Acid SCHEMBL28593338 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2AHSPD1 | |
| Myristyl Alcohol SCHEMBL27916759 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2AHSPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354547-B | Crystallization process of butamide citrate | 江西善渊药业有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-120006417-A | Antigen-fibrillated polyester monofilament and preparation method thereof | 浙江理工大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-113354547-B | Crystallization process of butamide citrate | 江西善渊药业有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-114755086-A | Sympathetic nerve immunohistochemical staining optimization method for adipose tissues of different parts of pig | 四川农业大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-108892613-B | Method for synthesizing tri-n-butyl citrate by using acid modified H-ZMS-5 type molecular sieve | 广东轻工职业技术学院 | 2021-02-19 | — | — | CN | disclosed |
| CN-107541186-B | Carbon nanotube film and ferrite composite wave-absorbing material and preparation method thereof | 天津师范大学 | 2020-04-10 | — | — | CN | disclosed |
| CN-108892613-A | A kind of method of the modified H-ZMS-5 type Zeolite synthesis tri-n-butyl citrate of acid | 广东轻工职业技术学院 | 2018-11-27 | — | — | CN | disclosed |
| CN-107541186-A | A kind of carbon nano-tube film and ferrite composite wave-suction material and preparation method thereof | 天津师范大学 | 2018-01-05 | — | — | CN | disclosed |
| CN-101643470-B | Alkyl ether derivatives or salts thereof | TOYAMA CHEMICAL CO LTD | 2012-08-01 | — | — | CN | disclosed |
| CN-101942733-B | Method for preparing netty environmental-friendly shell fabric by utilizing diversification process | ZHIDE MIAO | 2011-12-14 | — | — | CN | disclosed |
| CN-101942733-A | Method for preparing netty environmental-friendly shell fabric by utilizing diversification process | ZHIDE MIAO | 2011-01-12 | — | — | CN | disclosed |
| CN-101643470-A | Alkyl ether derivatives or salts thereof | TOYAMA CHEMICAL CO LTD JP | 2010-02-10 | — | — | CN | disclosed |
| WO-2009108748-A2 | METHODS FOR PRODUCING 1,3-PROPANEDIOL | NOVOZYMES A/S (DK) | 2009-09-03 | — | — | WO | disclosed |
| CN-100500662-C | Alkyl ether derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2009-06-17 | — | — | CN | disclosed |
| CN-1571786-A | Alkyl ether derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2005-01-26 | — | — | CN | disclosed |