Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096138 | 0.89 | TRPM8 (0.42) | TRPM8FFAR1HSD17B2MAPTPKM | |
| SCHEMBL3579316 | 0.79 | SSTR4 (0.41) | MAPTPKM | |
| SCHEMBL1096141 | 0.78 | TRPM8 (0.43) | TRPM8FFAR1HSD17B2MAPTPKM | |
| SCHEMBL7884856 | 0.76 | FFAR1 (0.48) | TRPM8FFAR1HSD17B2HTR2C | |
| SCHEMBL7884860 | 0.76 | FFAR1 (0.48) | TRPM8FFAR1HSD17B2HTR2C | |
| SCHEMBL3570815 | 0.73 | RPS6KB1 (0.38) | HTR2C | |
| SCHEMBL12496199 | 0.71 | TRPM8 (0.43) | TRPM8PKM | |
| SCHEMBL4067653 | 0.71 | SSTR4 (0.41) | MAPTPKM | |
| SCHEMBL1095799 | 0.70 | MAPT (0.38) | MAPTPKM | |
| SCHEMBL4094874 | 0.69 | SSTR4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085383-A1 | PIPERIDINE DERIVATIVES OR SALTS THEREOF | Astellas Pharma Inc. (JP) | 2009-08-05 | — | — | EP | disclosed |