⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15372466 | 0.69 | KDM4E (0.39) | — | |
| SCHEMBL8100707 | 0.65 | — | — | |
| SCHEMBL14327682 | 0.61 | TRPA1 (0.31) | — | |
| SCHEMBL25187984 | 0.61 | — | — | |
| SCHEMBL21061483 | 0.58 | — | — | |
| SCHEMBL6864335 | 0.57 | — | — | |
| SCHEMBL11954073 | 0.57 | — | — | |
| SCHEMBL15880263 | 0.57 | — | — | |
| SCHEMBL30873970 | 0.57 | — | — | |
| SCHEMBL293998 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013893-A1 | Process for the preparation of tetrahydrofuran-3-aldehydes | BAYER AG (DE) | 1980-08-06 | — | — | EP | claimed |
| US-20240016190-A1 | ROXBURGH ROSE AND COIX SEEDS COMPOSITE BEVERAGE AND PREPARATION METHOD THEREOF | GUIZHOU UNIVERSITY (CN) | 2024-01-18 | — | — | US | disclosed |
| CN-110627752-B | Preparation method of 3-aminomethyl tetrahydrofuran | 新发药业有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-109851594-B | Method for synthesizing 3-aminomethyl tetrahydrofuran by taking furan as raw material | 湖北远大富驰医药化工股份有限公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-107417648-B | Synthetic method of 3-aminomethyl tetrahydrofuran | 中国科学院兰州化学物理研究所 | 2020-05-19 | — | — | CN | disclosed |
| CN-110627752-A | Preparation method of 3-aminomethyl tetrahydrofuran | 新发药业有限公司 | 2019-12-31 | — | — | CN | disclosed |
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |
| CN-1441800-A | β3Adrenergic agonists | LILLY CO ELI (US) | 2003-09-10 | — | — | CN | disclosed |
| EP-0013893-A1 | Process for the preparation of tetrahydrofuran-3-aldehydes | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |
| EP-0013893-A1 | Process for the preparation of tetrahydrofuran-3-aldehydes | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |
| EP-0013893-A1 | Process for the preparation of tetrahydrofuran-3-aldehydes | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |