Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.65 |
| ▸ | OPRL1 | P41146 | 12/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409128 | 0.83 | OPRM1 (0.67) | OPRM1OPRL1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL17443464 | 0.80 | OPRM1 (0.63) | OPRM1OPRL1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL2839265 | 0.80 | OPRM1 (0.63) | OPRM1OPRL1SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL2339996 | 0.79 | OPRM1 (0.61) | OPRM1OPRL1SLC6A3SLC6A2 | |
| SCHEMBL517361 | 0.79 | OPRM1 (0.61) | OPRM1OPRL1SLC6A3LMNATSHR | |
| SCHEMBL3407373 | 0.79 | OPRL1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL4076511 | 0.77 | OPRL1 (0.59) | OPRM1OPRL1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL20866603 | 0.77 | OPRL1 (0.59) | OPRM1OPRL1SLC6A3SLC6A2 | |
| Ethylene SCHEMBL11099442 | 0.76 | OPRM1 (0.58) | OPRM1OPRL1SLC6A3LMNATSHR | |
| SCHEMBL3932959 | 0.76 | OPRM1 (0.62) | OPRM1OPRL1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |