Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 14/20 | 0.58 |
| ▸ | OPRL1 | P41146 | 14/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517361 | 0.97 | OPRM1 (0.61) | OPRM1OPRL1LMNATSHRKCNA3 | |
| SCHEMBL3409128 | 0.78 | OPRM1 (0.67) | OPRM1OPRL1LMNATSHRSLC6A3 | |
| Ethylene SCHEMBL11096261 | 0.76 | OPRM1 (0.46) | OPRM1OPRL1LMNATSHRKCNA3 | |
| SCHEMBL4081238 | 0.76 | OPRM1 (0.65) | OPRM1OPRL1LMNATSHRSLC6A3 | |
| SCHEMBL2839265 | 0.75 | OPRM1 (0.63) | OPRM1OPRL1SLC6A3 | |
| SCHEMBL17443464 | 0.75 | OPRM1 (0.63) | OPRM1OPRL1LMNATSHRSLC6A3 | |
| Ethylene SCHEMBL11087552 | 0.74 | LMNA (0.38) | OPRM1OPRL1LMNATSHRKCNA3 | |
| SCHEMBL3407373 | 0.73 | OPRL1 (1.00) | OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL2339996 | 0.73 | OPRM1 (0.61) | OPRM1OPRL1SLC6A3 | |
| Ethylene SCHEMBL11097350 | 0.73 | ALDH1A1 (0.44) | OPRM1OPRL1LMNATSHRKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |