Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMO | Q99835 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297167 | 0.92 | KDM4E (0.47) | KDM4EGAASMOPGRGPR183 | |
| SCHEMBL3290021 | 0.92 | KDM4E (0.48) | KDM4EGAASMOPGRGPR183 | |
| SCHEMBL3290350 | 0.91 | KDM4E (0.50) | KDM4EGAASMOPGRGPR183 | |
| SCHEMBL3291818 | 0.91 | GAA (0.48) | KDM4EGAASMOPGRGPR183 | |
| SCHEMBL3295277 | 0.91 | P2RX1 (0.47) | KDM4EGAAP2RX1EPHX2NPC1 | |
| SCHEMBL4074915 | 0.90 | APOB (0.51) | KDM4EGAAEPHX2ALDH1A1 | |
| SCHEMBL13329218 | 0.90 | NAMPT (0.46) | KDM4EGAASMOPGRGPR183 | |
| SCHEMBL3291608 | 0.89 | SMO (0.46) | KDM4EGAASMOPGRGPR183 | |
| SCHEMBL3297168 | 0.89 | GPR119 (0.47) | KDM4EGAASMOPGRGPR183 | |
| SCHEMBL3295473 | 0.89 | KDM4E (0.48) | KDM4EGAASMOPGRGPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753721-B1 | AROYL-O-PIPERIDINE DERIVATIVES FOR THE TREATMENT OF DIABETES-RELATED PROBLEMS | MERCK PATENT GMBH (DE) | 2009-08-05 | — | — | EP | claimed |