Ethylenediamine

Ethylenediamine

SCHEMBL408137

CCCCCCCCCCCCc1ccccc1S(=O)(=O)[O-].CCCCCCCCCCCCc1ccccc1S(=O)(=O)[O-].NCCN.NCCN.[Cu+2]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.47
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
HTR2A P28223 1/20 0.40
CA2 P00918 1/20 0.40
KCNH2 Q12809 6/20 0.39
TLR8 Q9NR97 2/20 0.39
BID P55957 3/20 0.38
MCL1 Q07820 3/20 0.38
BCL2L1 Q07817 2/20 0.38
BAK1 Q16611 2/20 0.38
KAT8 Q9H7Z6 2/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
EP300 Q09472 1/20 0.38
KAT2A Q92830 1/20 0.38
KAT2B Q92831 1/20 0.38
KAT5 Q92993 1/20 0.38
SAE1 Q9UBE0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylenediamine SCHEMBL30441324 1.00 LIPG (0.47) LIPGNR1H2NR1H3HTR2ACA2
SCHEMBL1374662 0.94 LIPG (0.53) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL31429057 0.94 LIPG (0.53) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL2494279 0.94 LIPG (0.53) LIPGNR1H2NR1H3CA2KCNH2
SCHEMBL1401303 0.94 LIPG (0.53) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL29435453 0.94 LIPG (0.53) LIPGNR1H2NR1H3KCNH2BID
Acetic Acid SCHEMBL9168699 0.93 LIPG (0.46) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL16895142 0.92 LIPG (0.54) LIPGNR1H2NR1H3KCNH2BID
Potassium Ion SCHEMBL23749193 0.91 LIPG (0.53) LIPGNR1H2NR1H3KCNH2BID
Lithium Ion SCHEMBL21822093 0.91 LIPG (0.53) LIPGNR1H2NR1H3KCNH2BID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US claimed
US-20090185867-A1 MARINE ANTI-FOULANT SYSTEM AND METHODS FOR USING SAME ASSET INTEGRITY MANAGEMENT SOLUTIONS, L.L.C., D/B/A AIMS INTERNATIONAL 2009-07-23 US claimed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US claimed
EP-4453057-A1 FOULING CONTROL COATING COMPOSITION PPG Coatings Europe B.V. (NL) 2024-10-30 EP disclosed
EP-4453112-A1 SELF ADHESIVE FOULING RELEASE COATING COMPOSITION PPG Coatings Europe B.V. (NL) 2024-10-30 EP disclosed
EP-3710539-B1 ANTIFOULING COMPOSITION JOTUN AS (NO) 2024-06-12 EP disclosed
WO-2024115765-A1 PROCESS JOTUN A/S (NO) 2024-06-06 WO disclosed
EP-4065649-B1 FOULING RELEASE COATING JOTUN AS (NO) 2024-01-03 EP disclosed
US-20230340278-A1 FOULING RELEASE COATING JOTUN A/S (NO) 2023-10-26 US disclosed
EP-3291678-B1 ANTIMICROBIAL MATERIALS EXHIBITING SYNERGISTIC EFFICACY CORNING INC (US) 2023-10-11 EP disclosed
WO-2023118476-A1 FOULING CONTROL COATING COMPOSITION PPG COATINGS EUROPE B.V. (NL) 2023-06-29 WO disclosed
US-5767171-A A MARINE, HYDROLYZABLE, ANTIFOULING, PROTECTIVE COATING BASED ON A POLYMER OF A TRIALKYLSILYL (METH)ACRYLATE AND AN ALKYLOXYALKYL (METH)ACRYLATE; NONCRACKING; UNIFORM EROSION; ADHESION NOF CORPORATION (JP) 1998-06-16 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed
EP-0714957-A1 Hydrolyzable self-polishing coating composition NOF CORPORATION (JP) 1996-06-05 EP disclosed
EP-0297505-B1 ANTIFOULING PAINT NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-09-02 EP disclosed
EP-0273457-B1 ANTIFOULING PAINT NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-07-08 EP disclosed
US-5116611-A Siloxane polymers NIPPON OIL AND FATS COMPANY LIMITED (JP) 1992-05-26 US disclosed
US-4898895-A Antifouling pain having a polyacrylate component with pendent silyl or siloxane groups NIPPON OIL AND FATS CO., LTD. (JP) 1990-02-06 US disclosed
EP-0297505-A2 Antifouling paint NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-01-04 EP disclosed
EP-0273457-A2 Antifouling paint NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-07-06 EP disclosed