Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL408137 | 0.93 | LIPG (0.47) | LIPGBIDMCL1PPARABCL2L1 | |
| Ethylenediamine SCHEMBL30441324 | 0.93 | LIPG (0.47) | LIPGBIDMCL1PPARABCL2L1 | |
| Bicarbonate SCHEMBL11369971 | 0.88 | LIPG (0.51) | LIPGBIDMCL1PPARABCL2L1 | |
| Urea SCHEMBL28313063 | 0.88 | LIPG (0.51) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL2494279 | 0.88 | LIPG (0.53) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL1374662 | 0.88 | LIPG (0.53) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL31429057 | 0.88 | LIPG (0.53) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL29435453 | 0.88 | LIPG (0.53) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL1401303 | 0.88 | LIPG (0.53) | LIPGBIDMCL1PPARABCL2L1 | |
| Monoethanolamine SCHEMBL9125956 | 0.87 | LIPG (0.48) | LIPGBIDMCL1PPARABCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434464-B1 | Transition-metal free Lubricant | ETHYL PETROLEUM ADDITIVES LTD (GB) | 1995-02-15 | — | — | EP | claimed |
| EP-0120665-B1 | SOLUBLE OIL CUTTING FLUID | The British Petroleum Company p.l.c. (GB) | 1987-05-13 | — | — | EP | claimed |
| US-5436284-A | Preventing attachment of organisms to surfaces of structures submerged in seawater | NOF CORPORATION (JP) | 1995-07-25 | — | — | US | disclosed |