SCHEMBL4081616

SCHEMBL4081616

CC(C)(C)[Si](C)(C)OC[CH]CCCC=O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.37
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL852468 0.79 DUT (0.40) HIF1ATSHR
SCHEMBL16830089 0.78 TSHR (0.39) TSHR
SCHEMBL26697567 0.78 TSHR (0.39) TSHR
SCHEMBL64584 0.78 DUT (0.30)
SCHEMBL5604846 0.77
SCHEMBL201004 0.77 DUT (0.39) HIF1ATSHR
SCHEMBL9628873 0.76
SCHEMBL2917304 0.76 TSHR (0.40) HIF1ATSHR
SCHEMBL9628880 0.76
SCHEMBL27241090 0.76 TSHR (0.40) HIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009042094-A2 HIV PROTEASE INHIBITORS MERCK & CO., INC. (US) 2009-04-02 WO disclosed