Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 5/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082053 | 0.87 | DRD2 (0.57) | ADRA1DADRA1AADRA1BFFAR4LMNA | |
| SCHEMBL3847613 | 0.86 | DRD2 (0.51) | ADRA1DDRD2DRD3DRD1HTR2A | |
| SCHEMBL3848840 | 0.86 | DRD2 (0.61) | DRD2DRD3DRD4HTR1AHTR2C | |
| SCHEMBL3849464 | 0.84 | FFAR4 (0.51) | ADRA1DADRA1AADRA1BFFAR4LMNA | |
| SCHEMBL3853456 | 0.83 | DRD2 (0.50) | DRD2DRD3MAPTL3MBTL1 | |
| SCHEMBL13630022 | 0.80 | DRD3 (0.57) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL4492199 | 0.80 | DRD3 (0.57) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL3851239 | 0.80 | DRD2 (0.64) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL13630261 | 0.78 | DRD3 (0.56) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL4490269 | 0.78 | DRD3 (0.56) | DRD2DRD3DRD4HTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473692-B2 | Sulfonamide derivatives as D3-receptor ligands | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-01-06 | — | — | US | claimed |