⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5982038 | 1.00 | — | — | |
| SCHEMBL15577940 | 0.85 | ALDH1A1 (0.43) | — | |
| SCHEMBL15577939 | 0.85 | ALDH1A1 (0.43) | — | |
| SCHEMBL4079399 | 0.74 | — | — | |
| SCHEMBL3398785 | 0.72 | — | — | |
| SCHEMBL1268269 | 0.72 | ALDH1A1 (1.00) | — | |
| SCHEMBL17988352 | 0.72 | — | — | |
| SCHEMBL9560049 | 0.72 | — | — | |
| SCHEMBL6863667 | 0.72 | — | — | |
| SCHEMBL15254109 | 0.72 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11117862-B2 | Methods of producing molindone and its salts | SUPERNUS PHARMACEUTICALS, INC. (US) | 2021-09-14 | — | — | US | claimed |
| US-20200262789-A1 | METHODS OF PRODUCING MOLINDONE AND ITS SALTS | SUPERNUS PHARMACEUTICALS, INC. (US) | 2020-08-20 | — | — | US | claimed |
| JP-60006651-A | — | — | None | — | — | JP | disclosed |
| CN-113321925-B | Composition for 3D printing, preparation method thereof, 3D printing method and device | 珠海赛纳三维科技有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114401722-A | Inhibitors of tyrosine kinases | 布里奇恩生物科学公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-113321925-A | Composition for 3D printing, preparation method thereof, 3D printing method and device | 珠海赛纳三维科技有限公司 | 2021-08-31 | — | — | CN | disclosed |
| JP-2009106923-A | CATALYTIC HYDROGENATION METHOD AND NOVEL CATALYST THEREFORE | EMMELLEN BIOTECH PHARMACEUTICALS LTD | 2009-05-21 | — | — | JP | disclosed |
| US-20090042888-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A | 2009-02-12 | — | — | US | disclosed |
| EP-1735266-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE 1-ERYTHRO-2-AMINO-1-PHENYL-1-PROPANOL | Emmellen Biotech Pharmaceuticals Limited (IN) | 2006-12-27 | — | — | EP | disclosed |
| US-7115591-B2 | Pyridazinone compounds as cyclooxygenase [COX] 2 inhibitorsfor gastrointestinal disorders | ABBOTT LABORATORIES (US) | 2006-10-03 | — | — | US | disclosed |
| US-7001895-B2 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LABORATORIES (US) | 2006-02-21 | — | — | US | disclosed |
| US-20030225276-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2003-12-04 | — | — | US | disclosed |
| US-20020028938-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2002-03-07 | — | — | US | disclosed |
| US-20020013318-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2002-01-31 | — | — | US | disclosed |
| US-6307047-B1 | PYRIDAZINONE COMPOUNDS; INHIBITORS OF CYCLOOXYGENASE-2 (COX-2); SELECTIVITY OF THESE COMPOUNDS FOR COX-2 MINIMIZES THE UNWANTED GI AND RENAL SIDE-EFFECTS SEEN WITH CURRENTLY MARKETED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ABBOTT LABORATORIES | 2001-10-23 | — | — | US | disclosed |
| EP-1124804-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024719-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2000-05-04 | — | — | WO | disclosed |
| JP-S606651-A | 1-HYDROXY-2-HYDROXYDIAZENIUMOXYDYLPROPANE AND ITS SALT | OJI KOONSUTAAC KK | 1985-01-14 | — | — | JP | disclosed |
| US-4338451-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1982-07-06 | — | — | US | disclosed |
| US-4250318-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1981-02-10 | — | — | US | disclosed |