Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 8/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279949 | 1.00 | HPGDS (0.56) | HPGDSCYP2A6CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL12279413 | 0.79 | HPGDS (0.71) | HPGDSCYP2A6CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL6691335 | 0.79 | CYP2A6 (0.58) | CYP2A6CYP3A4CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL15641472 | 0.78 | CYP2A6 (0.59) | HPGDSCYP2A6CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL30279938 | 0.78 | CYP2A6 (0.59) | HPGDSCYP2A6CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL12278098 | 0.76 | HPGDS (0.62) | HPGDSCYP2A6CYP3A4CYP2C9CYP2D6 | |
| Hydrochloric Acid SCHEMBL31452773 | 0.76 | CYP2A6 (0.58) | HPGDSCYP2A6CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL12278878 | 0.76 | HPGDS (0.55) | HPGDSCYP2A6CYP3A4CYP2C9CYP2E1 | |
| SCHEMBL9973686 | 0.75 | HPGDS (0.54) | HPGDSCYP2A6HSD17B1HSD17B2KDR | |
| SCHEMBL9973741 | 0.74 | HPGDS (0.56) | HPGDSCYP2A6CYP3A4CYP2C9HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850258-A | Synthesis method of masitinib | 东北林业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-115850258-A | Synthesis method of masitinib | 东北林业大学 | 2023-03-28 | — | — | CN | disclosed |
| US-20110065734-A1 | NOVEL BIFUNCTIONAL COMPOUNDS WHICH INHIBIT PROTEIN KINASES AND HISTONE DEACETYLASES | 4SC AG (DE) | 2011-03-17 | — | — | US | disclosed |
| EP-2060565-A1 | Novel bifunctional compounds which inhibit protein kinases and histone deacetylases | 4SC AG (DE) | 2009-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065734-A1 | NOVEL BIFUNCTIONAL COMPOUNDS WHICH INHIBIT PROTEIN KINASES AND HISTONE DEACETYLASES | HDAC1, HDAC11, MAP2K2 | HPGDS 1515/4885CYP2A6 4712/4885CYP3A4 4810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.